Hu Fan, Gong Ruijie, Chen Yexin, Zhang Jinxin, Hu Tian, Chen Yaqi, Zhang Kechun, Shang Meili, Cai Yong
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Xuhui Center for Disease Control and Prevention, Shanghai 200237, China.
Vaccines (Basel). 2021 Oct 21;9(11):1221. doi: 10.3390/vaccines9111221.
Since China's launch of the COVID-19 vaccination, the situation of the public, especially the mobile population, has not been optimistic. We investigated 782 factory workers for whether they would get a COVID-19 vaccine within the next 6 months. The participants were divided into a training set and a testing set for external validation conformed to a ratio of 3:1 with R software. The variables were screened by the Lead Absolute Shrinkage and Selection Operator (LASSO) regression analysis. Then, the prediction model, including important variables, used a multivariate logistic regression analysis and presented as a nomogram. The Receiver Operating Characteristic (ROC) curve, Kolmogorov-Smirnov (K-S) test, Lift test and Population Stability Index (PSI) were performed to test the validity and stability of the model and summarize the validation results. Only 45.54% of the participants had vaccination intentions, while 339 (43.35%) were unsure. Four of the 16 screened variables-self-efficacy, risk perception, perceived support and capability-were included in the prediction model. The results indicated that the model has a high predictive power and is highly stable. The government should be in the leading position, and the whole society should be mobilized and also make full use of peer education during vaccination initiatives.
自中国开展新冠病毒疫苗接种以来,公众尤其是流动人口的情况不容乐观。我们调查了782名工厂工人在未来6个月内是否会接种新冠病毒疫苗。使用R软件按照3:1的比例将参与者分为训练集和测试集用于外部验证。通过最小绝对收缩和选择算子(LASSO)回归分析筛选变量。然后,包含重要变量的预测模型采用多因素逻辑回归分析并以列线图呈现。进行受试者工作特征(ROC)曲线、柯尔莫哥洛夫-斯米尔诺夫(K-S)检验、提升检验和群体稳定性指数(PSI)以检验模型的有效性和稳定性并总结验证结果。只有45.54%的参与者有接种意愿,而339人(43.35%)不确定。筛选出的16个变量中的自我效能感、风险认知、感知支持和能力这4个变量被纳入预测模型。结果表明该模型具有较高的预测能力且高度稳定。政府应处于主导地位,动员全社会力量,并且在疫苗接种行动中充分利用同伴教育。