Ahmad Fauzi N A, Ireland A J, Sherriff M, Bandara H M H N, Su B
Paediatric Dentistry and Orthodontics Department, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia; Child Dental Health, Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol BS1 2LY, United Kingdom.
Child Dental Health, Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol BS1 2LY, United Kingdom.
Dent Mater. 2022 Jan;38(1):147-157. doi: 10.1016/j.dental.2021.10.019. Epub 2021 Nov 24.
To develop an aesthetic resin composite using a nitrogen-doped titanium dioxide (NTiO) filler that possesses antimicrobial properties against cariogenic bacteria.
N-TiO powder was manufactured by calcining commercial TiO with urea. Free radical release from the N-TiO powder under visible light irradiation was analysed using UV-Vis spectrophotometry. The N-TiO powder was incorporated into a dental resin and the photocatalytic activity assessed using a dye under both visible light and dark conditions. Using XTT assay to measure the cellular metabolic activity, the antibacterial properties of the N-TiO /resin composite discs were tested using Streptococcus mutans.
Doping nitrogen of TiO resulted in a band gap shift towards the visible light spectrum, which enabled the powder to release reactive oxygen species when exposed to visible light. When incorporated into a dental resin, the N-TiO/resin composite still demonstrated sustained release of reactive oxygen species, maintaining its photocatalytic activity and showing an antibacterial effect towards Streptococcus mutans under visible light conditions.
N-TiO filled resin composite shows great promise as a potential aesthetic resin based adhesive for orthodontic bonding.
研发一种使用掺氮二氧化钛（NTiO）填料的美学树脂复合材料，该填料对致龋细菌具有抗菌性能。
通过用尿素煅烧商用TiO来制造N-TiO粉末。使用紫外可见分光光度法分析N-TiO粉末在可见光照射下的自由基释放。将N-TiO粉末掺入牙科树脂中，并在可见光和黑暗条件下使用染料评估光催化活性。使用XTT测定法测量细胞代谢活性，使用变形链球菌测试N-TiO/树脂复合盘的抗菌性能。
TiO掺氮导致带隙向可见光谱移动，使该粉末在暴露于可见光时能够释放活性氧。当掺入牙科树脂中时，N-TiO/树脂复合材料仍表现出活性氧的持续释放，保持其光催化活性，并在可见光条件下对变形链球菌显示出抗菌作用。
N-TiO填充树脂复合材料作为一种潜在的用于正畸粘结的美学树脂基粘合剂显示出巨大的前景。
