Pan Shiqi, Lu Shuxin, Li Ruoyu, Zhang Xiangyu, Chen Weiyi
Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, P. R. China.
College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2022 Aug 25;39(4):749-758. doi: 10.7507/1001-5515.202112067.
The poor mechanical property and vulnerability to bacterial infections are the main problems in clinic for dental restoration resins. Based on this problem, the purpose of this study is to synthesize silver-titanium dioxide (Ag-TiO) nanoparticles with good photocatalytic properties, and add them to the composite resin to improve the mechanical properties and photocatalytic antibacterial capability of the resin. The microstructure and chemical composition of Ag-TiO nanoparticles and composite resins were characterized. The results indicated that Ag existed in both metallic and silver oxide state in the Ag-TiO, and Ag-TiO nanoparticles were uniformly dispersed in the resins. The results of mechanical experiments suggested that the mechanical properties of the composite resin were significantly improved due to the incorporation of Ag-TiO nanoparticles. The antibacterial results indicated that the Ag-TiO nanoparticle-filled composite resins exhibited excellent antibacterial activities under 660 nm light irradiation for 10 min due to the photocatalysis, and the Ag-TiO nanoparticle-filled composite resins could also exhibit excellent antibacterial activities after contact with bacteria for 24 h without light irradiation because of the release of Ag ions. In summary, this study provides a new antibacterial idea for the field of dental composite resins.
牙科修复树脂在临床上的主要问题是机械性能差和易受细菌感染。基于这一问题，本研究的目的是合成具有良好光催化性能的银-二氧化钛（Ag-TiO₂）纳米颗粒，并将其添加到复合树脂中，以提高树脂的机械性能和光催化抗菌能力。对Ag-TiO₂纳米颗粒和复合树脂的微观结构及化学成分进行了表征。结果表明，Ag-TiO₂中Ag以金属态和氧化银态存在，且Ag-TiO₂纳米颗粒均匀分散在树脂中。力学实验结果表明，由于加入了Ag-TiO₂纳米颗粒，复合树脂的机械性能得到显著提高。抗菌结果表明，由于光催化作用，填充Ag-TiO₂纳米颗粒的复合树脂在660 nm光照10 min下表现出优异的抗菌活性，并且由于Ag离子的释放，填充Ag-TiO₂纳米颗粒的复合树脂在无光照射下与细菌接触24 h后也能表现出优异的抗菌活性。综上所述，本研究为牙科复合树脂领域提供了一种新的抗菌思路。
