Yudaev Pavel, Chuev Vladimir, Klyukin Bogdan, Kuskov Andrey, Mezhuev Yaroslav, Chistyakov Evgeniy
Mendeleev University of Chemical Technology of Russia, Miusskaya Sq., 9, 125047 Moscow, Russia.
Belgorod National Research University, Pobedy Street, 85, 308015 Belgorod, Russia.
Polymers (Basel). 2022 Feb 22;14(5):864. doi: 10.3390/polym14050864.
This review aims to describe and critically analyze studies published over the past four years on the application of polymeric dental nanomaterials as antimicrobial materials in various fields of dentistry. Nanoparticles are promising antimicrobial additives to restoration materials. According to published data, composites based on silver nanoparticles, zinc(II), titanium(IV), magnesium(II), and copper(II) oxide nanoparticles, chitosan nanoparticles, calcium phosphate or fluoride nanoparticles, and nanodiamonds can be used in dental therapy and endodontics. Composites with nanoparticles of hydroxyapatite and bioactive glass proved to be of low efficiency for application in these fields. The materials applicable in orthodontics include nanodiamonds, silver nanoparticles, titanium(IV) and zinc(II) oxide nanoparticles, bioactive glass, and yttrium(III) fluoride nanoparticles. Composites of silver nanoparticles and zinc(II) oxide nanoparticles are used in periodontics, and nanodiamonds and silver, chitosan, and titanium(IV) oxide nanoparticles are employed in dental implantology and dental prosthetics. Composites based on titanium(IV) oxide can also be utilized in maxillofacial surgery to manufacture prostheses. Composites with copper(II) oxide nanoparticles and halloysite nanotubes are promising materials in the field of denture prosthetics. Composites with calcium(II) fluoride or phosphate nanoparticles can be used in therapeutic dentistry for tooth restoration.
本综述旨在描述和批判性分析过去四年发表的关于聚合物牙科纳米材料在牙科各个领域作为抗菌材料应用的研究。纳米颗粒是修复材料中很有前景的抗菌添加剂。根据已发表的数据，基于银纳米颗粒、锌（II）、钛（IV）、镁（II）和氧化铜（II）纳米颗粒、壳聚糖纳米颗粒、磷酸钙或氟化物纳米颗粒以及纳米金刚石的复合材料可用于牙科治疗和牙髓病学。含有羟基磷灰石和生物活性玻璃纳米颗粒的复合材料在这些领域的应用效率较低。适用于正畸学的材料包括纳米金刚石、银纳米颗粒、钛（IV）和氧化锌（II）纳米颗粒、生物活性玻璃以及氟化钇（III）纳米颗粒。银纳米颗粒和氧化锌（II）纳米颗粒的复合材料用于牙周病学，纳米金刚石以及银、壳聚糖和二氧化钛（IV）纳米颗粒用于牙种植学和牙科修复学。基于二氧化钛（IV）的复合材料也可用于颌面外科手术中制造假体。含有氧化铜（II）纳米颗粒和埃洛石纳米管的复合材料是义齿修复领域很有前景的材料。含有氟化钙（II）或磷酸纳米颗粒的复合材料可用于治疗牙科中的牙齿修复。
