College of Environmental Sciences and Engineering, The Key Laboratory of Water and Sediment Sciences, Ministry of Education, Peking University, Beijing, 100871, China.
State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems, International Joint Laboratory for Regional Pollution Control, Ministry of Education, Beijing, 100871, China.
Environ Sci Pollut Res Int. 2022 Apr;29(17):25209-25221. doi: 10.1007/s11356-021-17723-9. Epub 2021 Nov 27.
The occurrence of antibiotics in drinking water resources, like reservoirs, is of considerable concern due to their potential risks to ecosystem, human health, and antimicrobial resistance development. Here, we quantified 83 antibiotics in water and sediments of wet and dry seasons from the Miyun reservoir and its inflow rivers in Beijing, China. Twenty-four antibiotics were detected in water with concentrations of ND-11.6 ng/L and 19 antibiotics were observed in sediments with concentrations of ND-6.50 ng/g. Sulfonamides (SAs) were the dominated antibiotics in water in two seasons. SAs and quinolones (QNs) in wet season and macrolides (MLs) and QNs in dry season predominated in sediments. The reservoir and inflow rivers showed significant differences in antibiotic concentrations and compositions in water and sediments. As an important input source of reservoir, the river water showed significantly higher total antibiotic concentrations than those in the reservoir. In contrast, the reservoir sediments are the sink of antibiotics, and had higher total antibiotic concentrations compared with rivers. A prioritization approach based on the overall risk scores and detection frequencies of antibiotics was developed, and 3 (sulfaguanidine, anhydroerythromycin, and sulfamethoxazole) and 5 (doxycycline, sulfadiazine, clarithromycin, roxithromycin, and flumequine) antibiotics with high and moderate priority, respectively, were screened. The study provides a comprehensive insight of antibiotics in the Miyun Reservoir and its inflow rivers, and is significant for future monitoring and pollution mitigation of antibiotics.
抗生素在饮用水资源（如水库）中的存在引起了相当大的关注，因为它们对生态系统、人类健康和抗药性发展具有潜在风险。在这里，我们定量检测了来自中国北京密云水库及其入流河流的丰水期和枯水期的水和沉积物中的 83 种抗生素。在水中检测到 24 种抗生素，浓度为 ND-11.6ng/L；在沉积物中检测到 19 种抗生素，浓度为 ND-6.50ng/g。磺胺类药物（SAs）是两个季节水中的主要抗生素。在丰水期，磺胺类药物和喹诺酮类药物（QNs）占主导地位，而在枯水期，大环内酯类药物（MLs）和喹诺酮类药物占主导地位。水库和入流河流的水和沉积物中的抗生素浓度和组成存在显著差异。作为水库的一个重要输入源，河水的总抗生素浓度明显高于水库中的浓度。相比之下，水库沉积物是抗生素的汇，其总抗生素浓度高于河流。基于抗生素的综合风险评分和检出频率，开发了一种优先级排序方法，筛选出具有高优先级（磺胺胍、脱水红霉素和磺胺甲恶唑）和中优先级（强力霉素、磺胺嘧啶、克拉霉素、罗红霉素和氟甲喹）的 3 种和 5 种抗生素。本研究全面了解了密云水库及其入流河流中的抗生素，对抗生素的未来监测和污染缓解具有重要意义。
