Department of pediatric and child health, School of Medicine, College of Medicine and health sciences, University of Gondar, Gondar, Ethiopia.
Department of Anesthesia and critical care, School of Medicine, College of Medicine and health sciences, University of Gondar, Gondar, Ethiopia.
BMC Pediatr. 2021 Nov 27;21(1):525. doi: 10.1186/s12887-021-03019-x.
Perinatal asphyxia is one of the leading causes of neonatal mortality and morbidity in Ethiopia. Understanding associated factors of perinatal asphyxia are important to identify vulnerable groups and to improve care during the perinatal period. Thus, this study aimed to assess the prevalence and associated factors of perinatal asphyxia among newborns admitted to NICU at the Gondar University Comprehensive Specialized Hospital Northwest Ethiopia, Ethiopia.
Institutional based cross-sectional study was conducted on 364 newborns from November 2018 - August 2019. Data was collected using a structured and pre-tested questionnaire. It was then cleaned, coded, and entered using EPI INFO version 7, then analyzed with SPSS statistics version 20.0. Binary logistic regression analysis was used to identify variables with p < 0.2. An adjusted odds ratio (AOR) with a 95% CI and P-value of <0.05 was used to identify significantly associated variables with perinatal asphyxia.
The prevalence of perinatal asphyxia in this study was 19.8, 95%CI (15.9, 24.2). Absence of maternal formal education (AOR = 4.09, 95%CI: 1.25, 13.38), pregnancy-induced hypertension (AOR = 4.07, 95%CI: 1.76, 9.40), antepartum hemorrhage (AOR = 6.35, 95%CI: 1.68, 23.97), prolonged duration of labor (AOR = 3.69, 95%CI: 1.68, 8.10), instrumental delivery (AOR = 3.17, 95%CI: 1.22, 8.21), and meconium-stained amniotic fluid (AOR = 4.50, 95%CI: 2.19, 9.26) were significantly associated with perinatal asphyxia.
The prevalence rate of perinatal asphyxia in this study was comparable to other resource poor countries. The absence of maternal formal education, pregnancy-induced hypertension, and Antepartum hemorrhage, prolonged duration of labor, Instrumental assisted delivery, and meconium-stained amniotic fluid was having significant association with perinatal asphyxia in this study.
围产期窒息是埃塞俄比亚导致新生儿死亡和发病的主要原因之一。了解围产期窒息的相关因素对于确定脆弱群体和改善围产期护理非常重要。因此，本研究旨在评估埃塞俄比亚贡德尔大学综合专科医院新生儿重症监护病房（NICU）中新生儿围产期窒息的患病率及其相关因素。
本研究是 2018 年 11 月至 2019 年 8 月在埃塞俄比亚进行的一项基于机构的横断面研究，共纳入 364 名新生儿。采用结构化和预测试问卷收集数据。然后使用 EPI INFO 版本 7 进行清理、编码和输入，然后使用 SPSS 统计版本 20.0 进行分析。采用二元逻辑回归分析识别 p 值<0.2 的变量。采用调整后的优势比（AOR）和 95%置信区间（CI）及 P 值<0.05 来确定与围产期窒息有显著关联的变量。
本研究中围产期窒息的患病率为 19.8%（95%CI：15.9%，24.2%）。母亲未接受正规教育（AOR=4.09，95%CI：1.25，13.38）、妊娠高血压（AOR=4.07，95%CI：1.76，9.40）、产前出血（AOR=6.35，95%CI：1.68，23.97）、产程延长（AOR=3.69，95%CI：1.68，8.10）、器械分娩（AOR=3.17，95%CI：1.22，8.21）和胎粪污染羊水（AOR=4.50，95%CI：2.19，9.26）与围产期窒息显著相关。
本研究中围产期窒息的患病率与其他资源匮乏国家相当。母亲未接受正规教育、妊娠高血压、产前出血、产程延长、器械分娩和胎粪污染羊水与围产期窒息有显著关联。
