Alemu Abebe, Melaku Getnet, Abera Gerezgiher Buruh, Damte Ashenafi
Department of Midwifery, College of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
Department of Nursing, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia.
Pediatric Health Med Ther. 2019 Jul 24;10:69-74. doi: 10.2147/PHMT.S196265. eCollection 2019.
Globally, perinatal asphyxia is a significant contributing factor for neonatal morbidity and mortality. Thus, this study was aimed to assess the prevalence and associated factors with perinatal asphyxia among newborns in Dilla University referral hospital. A cross-sectional study was conducted among newborns in Dilla University referral hospital, Ethiopia from February to April 2017. Systematic random sampling techniques were used to enroll a total of 262 study subjects. Multivariate logistic regression analysis was used to identify factors associated with the perinatal asphyxia among newborns. Of the newborns, 32.8% had perinatal asphyxia, and factors associated significantly were anemia during pregnancy (adjusted OR=2.99, 95%CI: 1.07-8.35), chronic hypertension (adjusted OR=4.89, 95%CI: 1.16-20.72), meconium-stained amniotic fluid (adjusted OR=3.59, 95%CI: 1.74-7.42), and low birth weight newborns (adjusted OR=3.31, 95%CI: 1.308-8.37). Maternal anemia during pregnancy, chronic hypertension, meconium stained amniotic fluid, and low birth weight were significantly associated with perinatal asphyxia. Therefore, early screening and appropriate intervention during pregnancy, and intrapartum might reduce perinatal asphyxia among newborns.
在全球范围内,围产期窒息是新生儿发病和死亡的一个重要促成因素。因此,本研究旨在评估迪拉大学转诊医院新生儿围产期窒息的患病率及其相关因素。2017年2月至4月,在埃塞俄比亚迪拉大学转诊医院对新生儿进行了一项横断面研究。采用系统随机抽样技术共纳入262名研究对象。采用多因素logistic回归分析确定新生儿围产期窒息的相关因素。在这些新生儿中,32.8%患有围产期窒息,与之显著相关的因素有孕期贫血(校正比值比=2.99,95%置信区间:1.07 - 8.35)、慢性高血压(校正比值比=4.89,95%置信区间:1.16 - 20.72)、羊水胎粪污染(校正比值比=3.59,95%置信区间:1.74 - 7.42)和低体重新生儿(校正比值比=3.31,95%置信区间:1.308 - 8.37)。孕期母亲贫血、慢性高血压、羊水胎粪污染和低体重与围产期窒息显著相关。因此,孕期及产时的早期筛查和适当干预可能会降低新生儿的围产期窒息发生率。