First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, People's Republic of China.
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, 830011, Xinjiang, People's Republic of China.
BMC Infect Dis. 2021 Nov 27;21(1):1197. doi: 10.1186/s12879-021-06901-2.
This study mainly evaluates the clinical characteristics and chest chest computed tomography (CT) findings of AFB-positive and AFB-negative pulmonary tuberculosis (PTB) patients to explore the relationship between AFB-positive and clinico-radiological findings.
A retrospective analysis of 224 hospitalized tuberculosis patients from 2018 to 2020 was undertaken. According to the AFB smear results, they were divided into AFB-positive pulmonary tuberculosis (positive by Ziehl-Neelsen staining) and AFB-negative pulmonary tuberculosis and patients' CT results and laboratory test results were analyzed.
A total of 224 PTB patients were enrolled. AFB-positive (n = 94, 42%) and AFB-negative (n = 130, 58%). AFB-positive patients had more consolidation (77.7% vs. 53.8%, p < 0.01), cavity (55.3% vs. 34.6%, p < 0.01), calcification (38.3% vs. 20%, p < 0.01), bronchiectasis (7.5% vs. 1.5%, p < 0.05), bronchiarctia (6.4% vs. 0.8%, p < 0.05), and right upper lobe involvement (57.5% vs. 33.1%, p < 0.01), left upper lobe involvement (46.8% vs. 33.1%, p < 0.05) and lymphadenopathy (58.5% vs. 37.7%, p < 0.01).
The study found that when pulmonary tuberculosis patients have consolidation, cavity, upper lobe involvement and lymphadenopathy on chest CT images, they may have a higher risk of AFB-positive tuberculosis.
本研究主要评估 AFB 阳性和 AFB 阴性肺结核（PTB）患者的临床特征和胸部计算机断层扫描（CT）表现，以探讨 AFB 阳性与临床放射学表现之间的关系。
回顾性分析了 2018 年至 2020 年期间住院的 224 例肺结核患者。根据 AFB 涂片结果，将其分为 AFB 阳性肺结核（Ziehl-Neelsen 染色阳性）和 AFB 阴性肺结核，并分析患者的 CT 结果和实验室检查结果。
共纳入 224 例 PTB 患者。AFB 阳性（n=94，42%）和 AFB 阴性（n=130，58%）。AFB 阳性患者更易出现实变（77.7%比 53.8%，p<0.01）、空洞（55.3%比 34.6%，p<0.01）、钙化（38.3%比 20%，p<0.01）、支气管扩张（7.5%比 1.5%，p<0.05）、支气管狭窄（6.4%比 0.8%，p<0.05），以及右上叶受累（57.5%比 33.1%，p<0.01）、左上叶受累（46.8%比 33.1%，p<0.05）和淋巴结肿大（58.5%比 37.7%，p<0.01）。
本研究发现，当肺结核患者的胸部 CT 图像出现实变、空洞、上叶受累和淋巴结肿大时，他们可能有更高的 AFB 阳性肺结核风险。
