Department of Psychiatry, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; City International Hospital, Ho Chi Minh City, Viet Nam.
Department of Neurology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Department of Neurology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Viet Nam.
Epilepsy Behav. 2021 Dec;125:108446. doi: 10.1016/j.yebeh.2021.108446. Epub 2021 Nov 25.
Depression is a common mental disorder in people with epilepsy. Depression has a negative impact on medical and surgical treatment of epilepsy thus affecting the quality of life. Despite its high prevalence, depression has been under-recognized and treated improperly. It may also lead to missed work, increased healthcare system utilization, and higher direct medical costs.
This study aimed to evaluate the accuracy of the Vietnamese Patient Health Questionnaire (PHQ-9) as a screening tool for depression in people with epilepsy.
This cross-sectional study was conducted prospectively at epilepsy clinic at Nguyen Tri Phuong hospital, Ho Chi Minh City, Viet Nam from December 2019 to March 2020. A total of 91 adult people with epilepsy were recruited. After completing the Vietnamese PHQ-9 questionnaires, each participant was interviewed in a structured clinical interview for DSM-5 (SCID-5) to establish a diagnosis of major depressive disorder. The diagnostic accuracy of the PHQ-9 was assessed using diagnostic efficiency statistics compared with the gold standard structured interview.
The prevalence of major depression in this sample was 25.3%. The areas under receiver operating characteristic (ROC) curve index of PHQ-9 had an estimated value of 0.91. The PHQ-9 at a cutoff point of 8 had the great overall balance of sensitivity (87.0%) and specificity (82.4%). At the cutoff point of 10, PHQ-9 had a higher specificity of 94.1%, but a lower sensitivity of 78.0%.
The Vietnamese version PHQ-9 is an efficient and valid screening tool for depression in people with epilepsy in clinic settings.
抑郁症是癫痫患者中常见的精神障碍。抑郁症对癫痫的医疗和手术治疗有负面影响，从而影响生活质量。尽管抑郁症的患病率很高，但它一直未得到充分认识和不当治疗。它还可能导致旷工、增加医疗保健系统的利用和更高的直接医疗费用。
本研究旨在评估越南患者健康问卷（PHQ-9）作为癫痫患者抑郁筛查工具的准确性。
这是一项在 2019 年 12 月至 2020 年 3 月于胡志明市 Nguyen Tri Phuong 医院癫痫诊所进行的前瞻性横断面研究。共招募了 91 名成年癫痫患者。在完成越南 PHQ-9 问卷后，每位参与者都接受了 DSM-5 结构临床访谈（SCID-5）的结构化访谈，以建立重性抑郁障碍的诊断。使用与金标准结构访谈相比的诊断效率统计数据评估 PHQ-9 的诊断准确性。
该样本中重度抑郁症的患病率为 25.3%。PHQ-9 的接收器操作特征（ROC）曲线指数的面积估计值为 0.91。PHQ-9 的截止值为 8 时，具有较高的整体敏感性（87.0%）和特异性（82.4%）平衡。在截止值为 10 时，PHQ-9 具有较高的特异性（94.1%），但敏感性较低（78.0%）。
越南版 PHQ-9 是在临床环境中筛查癫痫患者抑郁的有效且有效的工具。
