• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[促进伤口修复和皮肤再生的新型生物活性材料]

[New bioactive materials for promoting wound repair and skin regeneration].

作者信息

Lyu G Z, Zhao P

机构信息

Engineering Research Center of the Ministry of Education for Wound Repair Technology, Treatment Center of Burns and Trauma, the Affiliated Hospital of Jiangnan University, Wuxi 214122, China.

出版信息

Zhonghua Shao Shang Za Zhi. 2021 Dec 20;37(12):1105-1109. doi: 10.3760/cma.j.cn501120-20211029-00373.

DOI:10.3760/cma.j.cn501120-20211029-00373
PMID:34839605
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11917273/
Abstract

The modulation of microenvironment is a key technology towards promoting wound repair and skin regeneration. In recent years, a series of new bioactive materials that modulate the microenvironment and cell behaviors have been developed, demonstrating highly efficient capability of inducing wound repair and skin appendage regeneration. This article summarizes the research development of related new bioactive materials and their mechanisms of action.

摘要

微环境调控是促进伤口修复和皮肤再生的关键技术。近年来,一系列能够调控微环境和细胞行为的新型生物活性材料得以开发,展现出高效诱导伤口修复和皮肤附属器再生的能力。本文综述了相关新型生物活性材料的研究进展及其作用机制。

相似文献

1
[New bioactive materials for promoting wound repair and skin regeneration].[促进伤口修复和皮肤再生的新型生物活性材料]
Zhonghua Shao Shang Za Zhi. 2021 Dec 20;37(12):1105-1109. doi: 10.3760/cma.j.cn501120-20211029-00373.
2
Fascia Layer-A Novel Target for the Application of Biomaterials in Skin Wound Healing.筋膜层——生物材料在皮肤创伤愈合应用中的新靶点
Int J Mol Sci. 2023 Feb 2;24(3):2936. doi: 10.3390/ijms24032936.
3
Bioactive Materials Promote Wound Healing through Modulation of Cell Behaviors.生物活性材料通过调节细胞行为促进伤口愈合。
Adv Sci (Weinh). 2022 Apr;9(10):e2105152. doi: 10.1002/advs.202105152. Epub 2022 Feb 9.
4
Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside.丝生物材料在创伤愈合和皮肤再生治疗中的应用:从实验室到临床。
Acta Biomater. 2020 Feb;103:24-51. doi: 10.1016/j.actbio.2019.11.050. Epub 2019 Dec 2.
5
Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration.工程化生物活性自修复抗菌外泌体水凝胶促进慢性糖尿病创面愈合和完全皮肤再生。
Theranostics. 2019 Jan 1;9(1):65-76. doi: 10.7150/thno.29766. eCollection 2019.
6
Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration.基于生物材料的机械调节促进无瘢痕伤口愈合和功能性皮肤附属器再生。
Mil Med Res. 2024 Feb 18;11(1):13. doi: 10.1186/s40779-024-00519-6.
7
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.可注射自组装肽纳米纤维水凝胶作为一种促进慢性伤口组织再生的生物活性 3D 支架。
Acta Biomater. 2021 Nov;135:100-112. doi: 10.1016/j.actbio.2021.08.008. Epub 2021 Aug 10.
8
[Microenvironment control is the only way to achieve perfect wound repair].微环境控制是实现完美伤口修复的唯一途径。
Zhonghua Shao Shang Za Zhi. 2020 Nov 20;36(11):1003-1008. doi: 10.3760/cma.j.cn501120-20201009-00429.
9
Skin-inspired elastomer-hydrogel Janus fibrous membrane creates a superior pro-regenerative microenvironment toward complete skin regeneration.受皮肤启发的弹性体-水凝胶双面纤维膜为完全皮肤再生创造了卓越的促再生微环境。
Biomater Adv. 2025 May;170:214227. doi: 10.1016/j.bioadv.2025.214227. Epub 2025 Feb 8.
10
LIPUS Responsive Dopamine-Modified PVDF Piezoelectric Nanofiber Membrane for Full-Thickness Skin Wound Healing.用于全层皮肤伤口愈合的低强度脉冲超声响应性多巴胺修饰聚偏氟乙烯压电纳米纤维膜
Int J Nanomedicine. 2025 May 1;20:5693-5707. doi: 10.2147/IJN.S496921. eCollection 2025.

本文引用的文献

1
Disrupting biological sensors of force promotes tissue regeneration in large organisms.破坏力的生物传感器可促进大型生物的组织再生。
Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z.
2
To Scar or Not to Scar.留疤还是不留疤。
N Engl J Med. 2021 Jul 29;385(5):469-471. doi: 10.1056/NEJMcibr2107204.
3
Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.机械激活的离子通道 Piezo1 调节巨噬细胞极化和刚性感知。
Nat Commun. 2021 May 31;12(1):3256. doi: 10.1038/s41467-021-23482-5.
4
Type 2 immunity induced by bladder extracellular matrix enhances corneal wound healing.膀胱细胞外基质诱导的 2 型免疫增强角膜伤口愈合。
Sci Adv. 2021 Apr 16;7(16). doi: 10.1126/sciadv.abe2635. Print 2021 Apr.
5
Negative-pressure wound therapy combined with artificial dermis (Terudermis) followed by split-thickness skin graft might be an effective treatment option for wounds exposing tendon and bone: A retrospective observation study.负压伤口疗法联合人工真皮(Terudermis),继以刃厚皮片移植,可能是一种有效治疗肌腱和骨外露创面的方法:一项回顾性观察研究。
Medicine (Baltimore). 2021 Apr 9;100(14):e25395. doi: 10.1097/MD.0000000000025395.
6
Human Wound and Its Burden: Updated 2020 Compendium of Estimates.人类创伤及其负担:2020 年最新估计综合报告。
Adv Wound Care (New Rochelle). 2021 May;10(5):281-292. doi: 10.1089/wound.2021.0026.
7
Modulation of Hypertrophic Scar Formation Using Amniotic Membrane/Electrospun Silk Fibroin Bilayer Membrane in a Rabbit Ear Model.在兔耳模型中使用羊膜/电纺丝素双层膜调节肥厚性瘢痕形成
ACS Biomater Sci Eng. 2019 Mar 11;5(3):1487-1496. doi: 10.1021/acsbiomaterials.8b01521. Epub 2019 Feb 14.
8
Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing.水凝胶支架激活适应性免疫反应可实现再生性伤口愈合。
Nat Mater. 2021 Apr;20(4):560-569. doi: 10.1038/s41563-020-00844-w. Epub 2020 Nov 9.
9
Fibroblast mechanosensing, SKI and Hippo signaling and the cardiac fibroblast phenotype: Looking beyond TGF-β.成纤维细胞机械传感、SKI与河马信号通路以及心脏成纤维细胞表型:超越转化生长因子-β的研究
Cell Signal. 2020 Dec;76:109802. doi: 10.1016/j.cellsig.2020.109802. Epub 2020 Oct 2.
10
Rapid printing of bio-inspired 3D tissue constructs for skin regeneration.用于皮肤再生的生物启发式3D组织构建体的快速打印。
Biomaterials. 2020 Nov;258:120287. doi: 10.1016/j.biomaterials.2020.120287. Epub 2020 Aug 14.