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海地高危妊娠妇女及其新生儿不良结局的风险因素

Risk factors for adverse outcomes in women with high-risk pregnancy and their neonates, Haiti.

作者信息

Schuurmans Jorien, Borgundvaag Emily, Finaldi Pasquale, Senat-Delva Rodnie, Desauguste Fedner, Badjo Colette, Lekkerkerker Michiel, Grandpierre Reynaldo, Lerebours Gerald, Ariti Cono, Lenglet Annick

机构信息

Médecins Sans Frontières Port-au-Prince Haiti Médecins Sans Frontières, Port-au-Prince, Haiti.

Médecins Sans Frontières Amsterdam Netherlands Médecins Sans Frontières, Amsterdam, The Netherlands.

出版信息

Rev Panam Salud Publica. 2021 Nov 1;45:e147. doi: 10.26633/RPSP.2021.147. eCollection 2021.

DOI:10.26633/RPSP.2021.147
PMID:34840557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8612597/
Abstract

OBJECTIVES

To determine the prevalence of maternal death, stillbirth and low birthweight in women with (pre-)eclampsia and complicated pregnancies or deliveries in Centre de Références des Urgences Obstétricales, an obstetric emergency hospital in Port-au-Prince, Haiti, and to identify the main risk factors for these adverse pregnancy outcomes.

METHODS

We conducted a retrospective cohort study of pregnant women admitted to Centre de Référence des Urgences Obstétricales between 2013 and 2018 using hospital records. Risk factors investigated were age group, type of pregnancy (singleton, multiple), type of delivery and use of antenatal care services.

RESULTS

A total of 31 509 women and 24 983 deliveries were included in the analysis. Among these, 204 (0.6%) maternal deaths (648 per 100 000 women giving birth), 1962 (7.9%) stillbirths and 11 008 (44.1%) low birthweight neonates were identified. Of all admissions, 10 991 (34.9%) were women with (pre-)eclampsia. Caesarean section significantly increased the risk of maternal death in the women with a complicated pregnancy and women with (pre-)eclampsia, but reduced the risk of stillbirth in such women. Not attending antenatal care was associated with a significantly higher risk of stillbirth (odds ratio (OR) 4.82; 95% confidence interval (CI) 3.55-6.55) and low birthweight (OR 1.40; 95% CI 1.05-1.86) for women with complicated pregnancies.

CONCLUSION

To prevent and treat pregnancy complications as early as possible, antenatal care attendance is crucial. Improving the quality of and access to antenatal care services and providing it free to all pregnant women in Haiti is recommended.

摘要

目的

确定海地太子港一家产科急诊医院——产科急诊参考中心中患(先兆)子痫及妊娠或分娩复杂的女性的孕产妇死亡、死产和低出生体重的发生率,并确定这些不良妊娠结局的主要风险因素。

方法

我们利用医院记录,对2013年至2018年间入住产科急诊参考中心的孕妇进行了一项回顾性队列研究。调查的风险因素包括年龄组、妊娠类型(单胎、多胎)、分娩类型和产前护理服务的使用情况。

结果

分析共纳入31509名女性和24983次分娩。其中,确定有204例(0.6%)孕产妇死亡(每10万名分娩女性中有648例)、1962例(7.9%)死产和11008例(44.1%)低出生体重新生儿。在所有入院患者中,10991例(34.9%)为患(先兆)子痫的女性。剖宫产显著增加了妊娠复杂女性和患(先兆)子痫女性的孕产妇死亡风险,但降低了此类女性的死产风险。对于妊娠复杂的女性,未接受产前护理与显著更高的死产风险(比值比(OR)4.82;95%置信区间(CI)3.55 - 6.55)和低出生体重风险(OR 1.40;95%CI 1.05 - 1.86)相关。

结论

为尽早预防和治疗妊娠并发症,产前护理至关重要。建议提高海地产前护理服务的质量和可及性,并为所有孕妇免费提供该服务。

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本文引用的文献

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BMJ Glob Health. 2020 Aug;5(8). doi: 10.1136/bmjgh-2020-002526.
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Hypertensive disorders in pregnancy and maternal and neonatal outcomes in Haiti: the importance of surveillance and data collection.妊娠高血压疾病与海地母婴和新生儿结局:监测和数据收集的重要性。
BMC Pregnancy Childbirth. 2019 Jun 20;19(1):208. doi: 10.1186/s12884-019-2361-0.
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Delayed access to emergency obstetrical care among preeclamptic and non-preeclamptic women in Port-Au-Prince, Haiti.海地太子港子痫前期和非子痫前期妇女获得紧急产科护理的延迟情况。
BMC Pregnancy Childbirth. 2018 Aug 20;18(1):337. doi: 10.1186/s12884-018-1961-4.
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Addressing the Child and Maternal Mortality Crisis in Haiti through a Central Referral Hospital Providing Countrywide Care.通过一家提供全国范围医疗服务的中央转诊医院应对海地的儿童和孕产妇死亡危机。
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Adverse maternal and fetal outcomes and deaths related to preeclampsia and eclampsia in Haiti.海地与子痫前期和子痫相关的孕产妇及胎儿不良结局和死亡情况。
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