Cerio Halle, Schad Laura A, Stewart Telisa M, Morley Christopher P
Department of Public Health & Preventive Medicine, State University of New York Upstate Medical University, Syracuse, NY.
Department of Public Health & Preventive Medicine, Department of Urology, and Department of Geriatrics, State University of New York Upstate Medical University, Syracuse, NY.
PRiMER. 2021 Sep 29;5:35. doi: 10.22454/PRiMER.2021.432215. eCollection 2021.
Vaccines against SARS-CoV-2 have been developed with unprecedented speed. The phased introduction of vaccines may be serving to offset the impact of new viral variants and policy relaxation. In order to assess the impact of vaccination, we examined a snapshot of vaccination rates across counties in a single state, at a single time point, comparing them with population-adjusted case counts.
We calculated descriptive statistics and bivariate correlations for vaccination rates and cases across counties in New York State (NYS). We conducted a linear regression using cases/100K population per NYS county, frozen at a single snapshot in time, as the outcome variable, predicted by percentage of each county's population (completed series/two doses), controlling for county population.
Percentages with one dose and with two doses were highly correlated (=.935, <.001) with one another. Both the one dose and two dose rates were negatively correlated with cases per 100K population (not significant). Population size was strongly correlated with cases per 100K (=.715, <.001). The two-dose vaccination rate was a significant negative predictor of cases per 100K population in NYS counties (β= -.866, =.031), with each percentage point of completed vaccination nearly equating to one case less in the daily count when controlling for county population size (β =2.732, <.001).
While variants may impact vaccine effectiveness, current vaccination efforts are helping forestall some cases in NYS. Widespread vaccination is still an important goal. Primary care providers, public officials, and public health scientists should continue to urgently promote and support vaccination efforts.
针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的疫苗以前所未有的速度研发出来。分阶段引入疫苗可能有助于抵消新病毒变种和政策放宽的影响。为了评估疫苗接种的影响,我们在单个时间点检查了一个州内各县的疫苗接种率快照,并将其与按人口调整的病例数进行比较。
我们计算了纽约州(NYS)各县疫苗接种率和病例数的描述性统计量及双变量相关性。我们进行了一项线性回归,将每个纽约州县每10万人口的病例数(在单个时间点固定)作为结果变量,由每个县人口的百分比(完成系列接种/两剂)进行预测,并控制县人口数。
单剂接种率和双剂接种率彼此高度相关(=0.935,<.001)。单剂接种率和双剂接种率与每10万人口的病例数均呈负相关(不显著)。人口规模与每10万人口的病例数高度相关(=0.715,<.001)。双剂疫苗接种率是纽约州各县每10万人口病例数的显著负预测因子(β = -0.866,P = 0.031),在控制县人口规模时,每完成一个百分点的疫苗接种,每日病例数几乎减少一例(β = 2.732,<.001)。
虽然病毒变种可能影响疫苗效力,但目前的疫苗接种工作有助于在纽约州预防一些病例。广泛接种疫苗仍然是一个重要目标。初级保健提供者、政府官员和公共卫生科学家应继续迫切地推动和支持疫苗接种工作。