Royal Free London NHS Foundation Trust, London, UK
BMJ Case Rep. 2021 Nov 29;14(11):e246553. doi: 10.1136/bcr-2021-246553.
Takotsubo cardiomyopathy is characterised by left ventricular apical ballooning, in the absence of coronary artery disease, and classically occurs at times of intense stress. Due to the striking preponderance of Takotsubo cardiomyopathy occurring in postmenopausal women, it has been postulated that female sex hormones may also be implicated in its pathogenesis. This case report describes the first case of Takotsubo cardiomyopathy associated with the initiation of dydrogesterone (a synthetic retroprogesterone) in a premenopausal woman.
应激性心肌病的特征为左心室心尖球囊样变，无冠状动脉疾病，经典发作于强烈应激时。由于绝经后妇女应激性心肌病的发生率显著增高，故推测女性性激素可能也参与了其发病机制。本病例报告描述了首例绝经前妇女应用地屈孕酮（一种合成的孕激素）起始治疗时发生应激性心肌病。
