Liu Hao, Dong Denghao, Chen Chunlin, Ye Jian
Department of Ophthalmology, Daping Hospital, Army Medical University, Chongqing 400042, China.
J Ophthalmol. 2021 Nov 20;2021:4074773. doi: 10.1155/2021/4074773. eCollection 2021.
To investigate the effects of two different surgical methods of implantable collamer lens (ICL) implantation on the operation time, visual outcomes, corneal endothelial cell count, and intraocular pressure (IOP).
This was a contralateral eye comparison study, a total of 192 eyes from 96 patients were included, and the two eyes from the same patient were randomly assigned to two groups (group 1 and group 2, with 96 eyes in each group). In group 1, after making the corneal incision, ophthalmic viscosurgical devices (OVDs) were first injected into the anterior chamber followed by ICL implantation. In group 2, the ICL was first implanted into the anterior chamber followed by OVDs injection. The operation time, uncorrected distance visual acuity, corrected distance visual acuity, spherical equivalent, corneal endothelial cell count, and IOP were recorded and analyzed.
The operative time in group 1 was significantly longer than that in group 2 ( = 0.002 < 0.05). There were significant differences between IOP measured 2 hours following surgery of the two groups ( = 0.026 < 0.05), Furthermore, the rate of IOP change 2 hours following the operation was significantly higher in group 1 than in group 2 ( = 0.019 < 0.05). There were significant differences in the anterior chamber angle 2 hours after surgery compared with that before surgery in both groups ( = 0.014 < 0.05 and = 0.029 < 0.05, respectively). No significant differences were observed in the other parameters measured (all > 0.05).
The two ICL implantation methods had similar clinical outcomes and effects on the corneal endothelial cell count. Additionally, the implantation of an intraocular lens prior to injecting OVDs reduces the operation time and lowers the rate of IOP rise in the early postoperative period, making it safe and effective for ICL implantation.
探讨两种不同的可植入式角膜接触镜（ICL）植入手术方法对手术时间、视力结果、角膜内皮细胞计数和眼压（IOP）的影响。
这是一项对侧眼比较研究，共纳入96例患者的192只眼，将同一患者的两只眼随机分为两组（第1组和第2组，每组96只眼）。第1组在制作角膜切口后，先向前房注入眼科粘弹剂（OVDs），然后植入ICL。第2组先将ICL植入前房，然后注入OVDs。记录并分析手术时间、未矫正远视力、矫正远视力、等效球镜度、角膜内皮细胞计数和眼压。
第1组的手术时间明显长于第2组（=0.002＜0.05）。两组术后2小时测量的眼压存在显著差异（=0.026＜0.05），此外，第1组术后2小时眼压变化率明显高于第2组（=0.019＜0.05）。两组术后2小时的前房角与术前相比均有显著差异（分别为=0.014＜0.05和=0.029＜0.05）。在测量的其他参数上未观察到显著差异（均＞0.05）。
两种ICL植入方法在临床结果和对角膜内皮细胞计数的影响方面相似。此外，在注入OVDs之前植入人工晶状体可缩短手术时间并降低术后早期眼压升高的速率，使其在ICL植入中安全有效。
