College of Education, Texas Tech University, Lubbock, TX, USA.
Department of Public Health, Texas Tech University Health Sciences Center, 3601 4th Street STOP 9430, Lubbock, TX, 79430, USA.
J Racial Ethn Health Disparities. 2023 Feb;10(1):32-42. doi: 10.1007/s40615-021-01194-2. Epub 2021 Nov 29.
Prescription opioid misuse (POM) is an important public health concern. Not many studies have evaluated factors influencing racial and ethnic differences in POM exclusively in young adolescents. We evaluated factors influencing the racial and ethnic differences in POM in a nationally representative sample of 8th- and 10th-grade (12-15 years old) US adolescents.
Data were from 107,786 adolescents who participated in the 2009-2019 Monitoring the Future survey. Logistic regression and mediation analysis were used to identify risk factors for POM and evaluate mediators of the association of race and ethnicity on the frequency of POM in the past year.
From 2009 to 2019, the prevalence of POM in the past year decreased from 3.2% to 1.8% (p = 0.032), with significant differences in POM trends by race and ethnicity. Overall, the prevalence was higher among non-Hispanic White adolescents (3.2%) than Hispanic (2.5%) and non-Hispanic Black adolescents (1.6%), p < 0.001. After adjustment for demographic, substance use, lifestyle, and family-related factors, the odds of POM were lower among Black (odds ratio (OR) = 0.81, 95% confidence interval (CI): 0.66-0.98) and Hispanic adolescents (OR = 0.64, CI: 0.55-0.74) compared to White adolescents. Illicit drug use and misuse of other prescription drugs together explained 77.2% and 47.3% of the racial and ethnic disparities in POM among Black and Hispanic adolescents, respectively.
In this study, significant racial and ethnic differences in the trends of POM were observed. Illicit drug use and misuse of other prescription drugs substantially explained the racial and ethnic disparities in POM among young adolescents.
处方阿片类药物滥用（POM）是一个重要的公共卫生问题。很少有研究专门评估影响青少年中阿片类药物滥用的种族和民族差异的因素。我们评估了在一个具有全国代表性的 8 至 10 年级（12-15 岁）美国青少年样本中，影响 POM 的种族和民族差异的因素。
数据来自于 2009 年至 2019 年参与“监测未来”调查的 107786 名青少年。使用逻辑回归和中介分析来确定 POM 的风险因素，并评估种族和民族对过去一年 POM 频率的关联的中介因素。
从 2009 年到 2019 年，过去一年 POM 的患病率从 3.2%降至 1.8%（p=0.032），不同种族和民族的 POM 趋势存在显著差异。总体而言，非西班牙裔白人青少年（3.2%）的患病率高于西班牙裔（2.5%）和非西班牙裔黑人青少年（1.6%），p<0.001。在调整人口统计学、物质使用、生活方式和家庭相关因素后，黑人（比值比（OR）=0.81，95%置信区间（CI）：0.66-0.98）和西班牙裔青少年（OR=0.64，CI：0.55-0.74）的 POM 几率低于白人青少年。非法药物使用和其他处方药物的误用共同解释了黑人青少年和西班牙裔青少年中 POM 种族和民族差异的 77.2%和 47.3%。
在这项研究中，观察到 POM 趋势存在显著的种族和民族差异。非法药物使用和其他处方药物的误用极大地解释了青少年中 POM 的种族和民族差异。
