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经皮冠状动脉介入术操作者特征及其与院内死亡率的关系。

Percutaneous Coronary Intervention Operator Profiles and Associations With In-Hospital Mortality.

机构信息

Division of Cardiology, Department of Medicine, University of Washington (J.A.D.).

Section of Cardiology, VA Puget Sound Health Care System, Seattle, WA (J.A.D.).

出版信息

Circ Cardiovasc Interv. 2022 Jan;15(1):e010909. doi: 10.1161/CIRCINTERVENTIONS.121.010909. Epub 2021 Dec 1.

Abstract

BACKGROUND

Percutaneous coronary intervention is performed by operators with differing experience, technique, and case mix. It is unknown if operator practice patterns impact patient outcomes. We sought to determine if a cluster algorithm can identify distinct profiles of percutaneous coronary intervention operators and if these profiles are associated with patient outcomes.

METHODS

Operators performing at least 25 annual procedures between 2014 and 2018 were clustered using an agglomerative hierarchical clustering algorithm. Risk-adjusted in-hospital mortality was compared between clusters.

RESULTS

We identified 4 practice profiles among 7706 operators performing 2 937 419 procedures. Cluster 1 (n=3345) demonstrated case mix and practice patterns similar to the national median. Cluster 2 (n=1993) treated patients with lower clinical acuity and were less likely to use intracoronary diagnostics, atherectomy, and radial access. Cluster 3 (n=1513) had the lowest case volume, were more likely to work at rural hospitals, and cared for a higher proportion of patients with ST-segment-elevation myocardial infarction and cardiogenic shock. Cluster 4 (n=855) had the highest case volume, were most likely to treat patients with high anatomic complexity and use atherectomy, intracoronary diagnostics, and mechanical support. Compared with cluster 1, adjusted in-hospital mortality was similar for cluster 2 (estimated difference, -0.03 [95% CI, -0.10 to 0.04]), higher for cluster 3 (0.14 [0.07-0.22]), and lower for cluster 4 (-0.15 [-0.24 to -0.06]).

CONCLUSIONS

Distinct percutaneous coronary intervention operator profiles are differentially associated with patient outcomes. A phenotypic approach to physician assessment may provide actionable feedback for quality improvement.

摘要

背景

经皮冠状动脉介入治疗由经验、技术和病例组合不同的操作者进行。尚不清楚操作者的实践模式是否会影响患者的结局。我们试图确定聚类算法是否可以识别出不同的经皮冠状动脉介入治疗操作者的特征,并确定这些特征是否与患者的结局相关。

方法

对 2014 年至 2018 年期间每年至少进行 25 例手术的操作者使用凝聚层次聚类算法进行聚类。比较了聚类之间的风险调整院内死亡率。

结果

我们在 7706 名进行 2937419 例手术的操作者中确定了 4 种操作模式。聚类 1(n=3345)的病例组合和操作模式与全国中位数相似。聚类 2(n=1993)的患者临床病情较轻,较少使用冠状动脉内诊断、旋切术和桡动脉入路。聚类 3(n=1513)的病例量最低,更可能在农村医院工作,治疗 ST 段抬高型心肌梗死和心源性休克患者的比例更高。聚类 4(n=855)的病例量最高,最有可能治疗解剖结构复杂的患者,使用旋切术、冠状动脉内诊断和机械支持。与聚类 1 相比,聚类 2 的调整后院内死亡率相似(估计差值,-0.03[95%CI,-0.10 至 0.04]),聚类 3 较高(0.14[0.07 至 0.22]),聚类 4 较低(-0.15[-0.24 至-0.06])。

结论

不同的经皮冠状动脉介入治疗操作者特征与患者的结局有不同的相关性。对医生的评估采用表型方法可能为质量改进提供可行的反馈。

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