Evangelista Deborah Gollner, Malaguti Carla, Meirelles Felipe de Azevedo, de Jesus Luciana Angélica da Silva, José Anderson, Cabral Leandro Ferracini, Silva Vanessa Cardoso, Cabral Laura Alves, Oliveira Cristino Carneiro
Post-Graduate Research Program on Rehabilitation Sciences and Physical Function Performance, Faculty of Physiotherapy, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Department of Physiotherapy, Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil.
COPD. 2021 Dec;18(6):630-636. doi: 10.1080/15412555.2021.2005012. Epub 2021 Nov 30.
Long-term oxygen therapy (LTOT) reduces hypoxaemia and mitigate systemic alterations in chronic obstructive pulmonary disease (COPD), however, it is related to inactivity and social isolation. Social participation and its related factors remain underexplored in individuals on LTOT. This study investigated social participation in individuals with COPD on LTOT and its association with dyspnoea, exercise capacity, muscle strength, symptoms of anxiety and depression, and quality of life. The Assessment of Life Habits (LIFE-H) assessed social participation. The modified Medical Research Council dyspnoea scale, the 6-Minute Step test (6MST) and handgrip dynamometry were used for assessments. In addition, participants responded to the Hospital Anxiety and Depression Scale (HADS) and the Chronic Respiratory Questionnaire (CRQ). Correlation coefficients and multivariate linear regression analyses were applied. Fifty-seven participants with moderate to very severe COPD on LTOT were included (71 ± 8 years, FEV: 40 ± 17%predicted). Social participation was associated with dyspnoea (=-0.46, < 0.01), exercise capacity ( = 0.32, = 0.03) and muscle strength ( = 0.25, = 0.05). Better participation was also associated with fewer depression symptoms (=-0.40, < 0.01) and a better quality of life ( = 0.32, = 0.01). Dyspnoea was an independent predictor of social participation ( < 0.01) on regression models. Restricted social participation is associated with increased dyspnoea, reduced muscle strength and exercise capacity. Better participation is associated with fewer depression symptoms and better quality of life in individuals with COPD on LTOT.
长期氧疗（LTOT）可减轻慢性阻塞性肺疾病（COPD）患者的低氧血症并缓解全身改变，然而，它与活动减少和社会隔离有关。LTOT患者的社会参与及其相关因素仍未得到充分研究。本研究调查了接受LTOT的COPD患者的社会参与情况及其与呼吸困难、运动能力、肌肉力量、焦虑和抑郁症状以及生活质量的关联。生活习惯评估量表（LIFE-H）用于评估社会参与情况。采用改良的医学研究委员会呼吸困难量表、6分钟步行试验（6MST）和握力测定进行评估。此外，参与者还回答了医院焦虑抑郁量表（HADS）和慢性呼吸问卷（CRQ）。应用相关系数和多元线性回归分析。纳入了57名接受LTOT的中度至非常重度COPD患者（71±8岁，FEV：预测值的40±17%）。社会参与与呼吸困难（=-0.46，<0.01）、运动能力（=0.32，=0.03）和肌肉力量（=0.25，=0.05）相关。更好的参与度还与较少的抑郁症状（=-0.40，<0.01）和更好的生活质量（=0.32，=0.01）相关。在回归模型中，呼吸困难是社会参与的独立预测因素（<0.01）。社会参与受限与呼吸困难增加、肌肉力量和运动能力降低有关。在接受LTOT的COPD患者中，更好的参与度与较少的抑郁症状和更好的生活质量相关。
