Lawrence Amelia S, Stoddard David G, Czyz Craig N, Richardson Thomas E, Michels Kevin S
Elson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
Department of Otorhinolaryngology, Columbia Surgical Specialists, Spokane, Washington, USA.
Orbit. 2023 Jun;42(3):332-335. doi: 10.1080/01676830.2021.2006722. Epub 2021 Nov 30.
Patients with COVID-19 have been reported to have elevated coagulation factors, which is a well-documented cause of venous thromboembolism events such as deep vein thrombosis and pulmonary embolism. Other venous thrombotic events, however, such as cavernous sinus thrombosis (CST) have been less commonly observed, specifically in combination with primary orbital cellulitis. Due to its unique anatomic location, the cavernous sinus is susceptible to thrombophlebitis processes including septic thrombosis and thrombosis most commonly from sinusitis. Many studies have shown that in the antibiotic era thromboembolic events of the cavernous sinus are less common due to infection spread from the orbit or facial region. This case report describes a 17-year-old COVID-19 positive male who presented with a left-sided primary orbital cellulitis with CST without radiographic evidence of ipsilateral sinus disease.
据报道，新冠肺炎患者的凝血因子升高，这是深静脉血栓形成和肺栓塞等静脉血栓栓塞事件的一个有充分记录的原因。然而，其他静脉血栓形成事件，如海绵窦血栓形成（CST），则较少见，特别是与原发性眼眶蜂窝织炎同时出现时。由于其独特的解剖位置，海绵窦易发生血栓性静脉炎，包括脓毒性血栓形成和最常见于鼻窦炎的血栓形成。许多研究表明，在抗生素时代，由于感染从眼眶或面部区域扩散，海绵窦的血栓栓塞事件较少见。本病例报告描述了一名17岁的新冠肺炎阳性男性，他表现为左侧原发性眼眶蜂窝织炎合并CST，而同侧鼻窦疾病无影像学证据。
