Sakai Kuniyoshi L
Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo.
Brain Nerve. 2021 Dec;73(12):1327-1331. doi: 10.11477/mf.1416201943.
The musician Ludwig van Beethoven suffered from hearing impairment and abdominal pain beginning in his mid-twenties. Lead intoxication can cause both of neural symptoms and digestive disorders. Lead was often present in poor-quality wines at that period, and thus Beethoven could have ingested a large amount of lead through daily wine consumption. His auditory processing disorder was merely a deficit in the lower level bottom-up processing of musical sounds or voice inputs, and probably did not affect higher level top-down processing, such as the representation of auditory imagery and composition.
音乐家路德维希·凡·贝多芬在二十多岁时开始出现听力障碍和腹痛。铅中毒可导致神经症状和消化系统紊乱。在那个时期,劣质葡萄酒中常常含有铅,因此贝多芬可能通过日常饮酒摄入了大量的铅。他的听觉加工障碍仅仅是音乐声音或语音输入的低级自下而上加工中的缺陷,可能并未影响高级自上而下的加工,如听觉意象的表征和作曲。