Sobkowska Daria, Micek Iwona, Urbańska Maria, Seraszek-Jaros Agnieszka, Nowak Gerard, Zaprutko Lucjusz, Czajkowski Rafał, Adamski Zygmunt, Gornowicz-Porowska Justyna
Department of Practical Cosmetology and Prevention of Skin Diseases, Poznan University of Medical Sciences, Poznan, Poland.
Chair of Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Ludwik Rydygier Medical College in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Postepy Dermatol Alergol. 2021 Oct;38(5):798-803. doi: 10.5114/ada.2021.110078. Epub 2021 Nov 5.
Sweet whey is known for its various pharmacological uses as an anti-inflammatory and antioxidant agent. This is because whey proteins accelerate the release of bioactive peptides, increase the level of intracellular glutathione and the production of interleukin IL-8. However, the potential skin care effects of whey, especially in its unprocessed state, are still not clear.
To evaluate the cosmetic features of sweet whey baths and wet wraps on human skin.
Thirteen healthy Caucasian adult females with no dermatological diseases were examined. We used the Courage-Khazaka MPA-9 device to evaluate the effects of sweet whey baths/wet wraps on skin hydration, transepidermal water loss (TEWL) and melanin and erythema index and pH level in human skin.
It appeared that bathing in the sweet whey solution significantly improved the barrier function of the skin in comparison with tap water treated control area on the face cheek as well as on the forearm by decreasing the value of transepidermal water loss with statistical significance. Skin hydration was enhanced only on the facial skin. No significant differences concerning other parameters were observed.
We showed that sweet whey may have decreased the TEWL level and fixed the barrier function of epidermis in this way. It seems that a bath solution with sweet whey is well tolerated and may promote local blood circulation without affecting the pH value of the skin.
甜乳清因其作为抗炎和抗氧化剂的多种药理用途而闻名。这是因为乳清蛋白能加速生物活性肽的释放，提高细胞内谷胱甘肽水平并促进白细胞介素IL - 8的产生。然而，乳清的潜在护肤效果，尤其是未加工状态下的，仍不明确。
评估甜乳清浴和湿敷对人体皮肤的美容特性。
对13名无皮肤病的健康白种成年女性进行了检查。我们使用Courage - Khazaka MPA - 9设备评估甜乳清浴/湿敷对人体皮肤水合作用、经表皮水分流失（TEWL）、黑色素和红斑指数以及pH值的影响。
与脸颊和前臂上用自来水处理的对照区域相比，在甜乳清溶液中沐浴通过降低经表皮水分流失值，显著改善了皮肤的屏障功能，具有统计学意义。仅面部皮肤的水合作用增强。在其他参数方面未观察到显著差异。
我们表明甜乳清可能降低了TEWL水平并以此修复了表皮的屏障功能。含甜乳清的沐浴溶液似乎耐受性良好，且可能促进局部血液循环而不影响皮肤的pH值。
