Fundació Puigvert. Autonomous University of Barcelona. Barcelona. Spain.
Fundació Puigvert. Autonomous University of Barcelona. Barcelona. Spain. Department of Urology. Humanitas Clinical and Research Institute IRCCS. Rozzano. Italy.
Arch Esp Urol. 2021 Dec;74(10):970-978.
Nowadays, Robotic assistedkidney transplantation (RAKT) is considered a lessinvasive alternative to the Open Kidney Transplantation(OKT) with several advantages such as image magnification,3D vision and articulated instruments and with arelatively short learning curve for an experienced surgeon.RAKT has shown comparable outcomes with theOKT literature data in terms of surgical and functionalresults. RAKT may decrease the complication rate, meanhospital stay, postoperative pain, and also improve aestheticoutcomes. The aim of this study was to perform asystematic review of the literature on this novel approachof KT.
A systematic review was performed in accordance with the Preferred ReportingItems for Systematic Reviews and Meta-Analyses (PRISMA)statement. The search was conducted using the databases PubMed/Medline, including as outcomes: (1) indications, (2) step-by-step technique for RAKT, (3) RAKT in special cases (4) surgical and functional outcomes,and (5) future perspectives in RAKT.
The indications for RAKT are expanding, sothat including obese recipients, graft with multiple vesselsand graft from deceased donor. To date, the two absolute contraindications to RAKT are patients unfitfor pneumoperitoneum and presenting advanced atheromatic plaques where vessel clamping could result challenging. As far as the outcomes, the surgical and functional results are in line with the OKT experience.Complication rate is low in RAKT, particularly in terms of arterial and venous thrombosis (1%), lymphocele (3%),ureteral stricture (2%), and wound infection (0.3%). Arobotic assisted kidney auto-transplantation (RAKAT) has been recently described, as novel approach in case of complex proximal benign ureteral stenosis. Despite great advances in this field, some limits still need to be approached such as the modality to main tain the graft to a constant low temperature ( <20 ºC) and to find the proper location of arteriotomy in advanced atheromatic disease without the tactile feedback.
The present review has confirmed that RAKT is as safe and feasible as OKT with comparable surgical and functional results. Complication rate is lower in RAKT than OKT and the indications are expanding quickly. Furthermore, new technologies are being introduced in order to improve the surgical performances and to expand more the indications for robotic surgery.However, a prospective randomized study in order to compare RAKT versus OKT is still required.
如今,机器人辅助肾脏移植(RAKT)被认为是一种比开放式肾脏移植(OKT)更具侵入性的替代方法,具有图像放大、3D 视觉和铰接式器械等优势,且对于经验丰富的外科医生来说,学习曲线相对较短。RAKT 在手术和功能结果方面与 OKT 文献数据相当。RAKT 可能会降低并发症发生率、平均住院时间、术后疼痛,并且还可以改善美容效果。本研究旨在对 KT 的这一新方法进行系统评价。
根据系统评价和荟萃分析的首选报告项目(PRISMA)声明进行了系统评价。使用 PubMed/Medline 数据库进行了搜索,包括以下结果:(1)适应证,(2)RAKT 的逐步技术,(3)RAKT 在特殊情况下,(4)手术和功能结果,(5)RAKT 的未来展望。
RAKT 的适应证正在扩大,因此包括肥胖受者、多血管移植物和已故供体的移植物。迄今为止,RAKT 的两个绝对禁忌证是不适合气腹和存在晚期动脉粥样硬化斑块的患者,因为血管夹闭可能会带来挑战。就手术和功能结果而言,RAKT 的结果与 OKT 经验相符。RAKT 的并发症发生率较低,尤其是动脉和静脉血栓形成(1%)、淋巴囊肿(3%)、输尿管狭窄(2%)和伤口感染(0.3%)。最近描述了一种新型的机器人辅助肾脏自体移植(RAKAT),用于治疗复杂的近端良性输尿管狭窄。尽管在这一领域取得了巨大进展,但仍需要解决一些限制,例如保持移植物恒定低温(<20°C)的方式,以及在没有触觉反馈的情况下,在晚期动脉粥样硬化疾病中找到合适的动脉切开位置。
本综述证实,RAKT 与 OKT 一样安全可行,手术和功能结果相当。RAKT 的并发症发生率低于 OKT,适应证正在迅速扩大。此外,正在引入新技术以提高手术性能,并进一步扩大机器人手术的适应证。然而,仍需要一项前瞻性随机研究来比较 RAKT 与 OKT。