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开放与机器人辅助肾移植:欧洲泌尿外科学会(EAU)-青年泌尿外科医生(YAU)肾脏移植工作组的系统评价。

Open versus robotic-assisted kidney transplantation: A systematic review by the European Association of Urology (EAU) - Young Academic Urologists (YAU) Kidney Transplant Working Group.

机构信息

Uro-oncology and Kidney Transplant Unit, Department of Urology at "Fundació Puigvert" Hospital, Autonoma University of Barcelona, Barcelona, Spain.

Department of Urology and Kidney Transplantation, Rangueil University Hospital, Toulouse, France.

出版信息

Actas Urol Esp (Engl Ed). 2023 Oct;47(8):474-487. doi: 10.1016/j.acuroe.2023.03.003. Epub 2023 Mar 24.

Abstract

INTRODUCTION

In the last 20 years, robotic assisted procedures were evaluated in the field of kidney transplantation to provide a mini-invasive approach for this particularly fragile population. As a relatively new issue, few studies compared open kidney transplantation (OKT) and robotic-assisted kidney transplantation (RAKT), mostly in small cohorts. To improve current knowledge, we wanted here to gather comparative data of OKT vs RAKT in a systematic review.

METHODS

A systematic review was performed according to preferred reporting items for systematic reviews and meta-analyses. Medline, Embase, and Cochrane databases were searched to identify all studies reporting post-operative outcomes of RAKT versus OKT.

RESULTS

A total of 2136 patients in 13 studies were included. Median recipient age was 42.6 years (OKT: 43.5 years and RAKT: 40.3 years). Median preemptive kidney transplantation rate was 27.1 % (OKT: 23.3 % and RAKT: 33.2 %). Median total operative time and rewarming were respectively: 235 and 49 min in OKT population; 250 and 60 min in RAKT population. Post-operative complications rates were: 26.2 % in OKT population and 17.8 % in RAKT population. Delayed graft function rates were: 4.9 % in OKT population and 2.3 in RAKT population. Mid-term functional outcomes, patient and graft survival were similar in OKT and RAKT population.

CONCLUSION

This systematic review showed that RAKT may be associated with a lower incidence of delayed graft function and post-operative surgical complications and similar mid-term functional outcomes, patient and graft survival, compared to OKT for end-stage renal disease patients.

摘要

介绍

在过去的 20 年中,机器人辅助手术已在肾移植领域得到评估,为这一特别脆弱的人群提供微创方法。作为一个相对较新的问题,很少有研究比较开放肾移植(OKT)和机器人辅助肾移植(RAKT),而且大多数研究的样本量都较小。为了提高现有知识水平,我们希望在这里对 OKT 和 RAKT 进行系统评价,以收集比较数据。

方法

根据系统评价和荟萃分析的首选报告项目进行了系统评价。检索了 Medline、Embase 和 Cochrane 数据库,以确定所有报告 RAKT 与 OKT 术后结果的研究。

结果

共有 13 项研究中的 2136 名患者纳入本研究。中位受者年龄为 42.6 岁(OKT:43.5 岁;RAKT:40.3 岁)。中位预先性肾移植率为 27.1%(OKT:23.3%;RAKT:33.2%)。中位总手术时间和复温时间分别为:OKT 组为 235 分钟和 49 分钟;RAKT 组为 250 分钟和 60 分钟。术后并发症发生率分别为:OKT 组为 26.2%;RAKT 组为 17.8%。延迟肾功能恢复率分别为:OKT 组为 4.9%;RAKT 组为 2.3%。中期功能结果、患者和移植物存活率在 OKT 和 RAKT 组之间相似。

结论

本系统评价表明,与 OKT 相比,RAKT 可能与较低的迟发性移植物功能障碍和术后手术并发症发生率以及相似的中期功能结果、患者和移植物存活率相关,适用于终末期肾病患者。

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