Universidade Federal de Pernambuco, Recife, Brasil.
Centro de Ciências da Saúde, Universidade Federal de Pernambuco, Recife, Brasil.
Cad Saude Publica. 2021 Nov 22;37(11):e00228520. doi: 10.1590/0102-311X00228520. eCollection 2021.
This study aimed to compare the anthropometric measurements and body proportionalities of neonates born before the Zika virus epidemic with those born during this period. We compared 958 neonates born during the pre-Zika epidemic with 264 neonates born during the epidemic period. The newborns had their head circumference, weight, and length classified according to the Fenton & Kim growth chart. We considered disproportionate those individuals that presented microcephaly and adequate weight or length for sex and gestational age, and those whose head circumferences were lower than the ratio ((length / 2) + 9.5) - 2.5cm. We estimated the frequencies of Zika positivity and brain imaging findings among neonates with microcephaly born during the epidemic period, concerning the anthropometric and body proportionality parameters. Low weight and proportionate microcephaly were similar among newborns from both periods. However, the frequencies of newborns with microcephaly with a very low length and disproportionate microcephaly were higher among the neonates of the epidemic period with brain abnormalities and positive for Zika virus. We conclude that, at birth, the disproportion between head circumference and length can be an indicator of the severity of microcephaly caused by congenital Zika.
本研究旨在比较寨卡病毒流行前和流行期间出生的新生儿的人体测量学测量值和身体比例。我们比较了 958 名在寨卡流行前出生的新生儿和 264 名在流行期间出生的新生儿。根据 Fenton & Kim 生长图表，对新生儿的头围、体重和长度进行分类。我们认为那些头围低于比例 ((长度 / 2) + 9.5) - 2.5cm，同时体重和长度对于性别和胎龄来说是合适的，具有小头畸形的新生儿是不成比例的。我们考虑了在流行期间出生的小头畸形新生儿的寨卡病毒阳性率和脑成像结果，以及与人体测量学和身体比例参数有关的情况。在两个时期出生的新生儿中，体重低和比例适当的小头畸形的发生率相似。然而，在具有脑异常和寨卡病毒阳性的流行期间的小头畸形新生儿中，头围和长度不成比例的小头畸形新生儿的频率更高。我们得出结论，在出生时，头围和长度之间的不成比例可能是先天性寨卡病毒引起的小头畸形严重程度的一个指标。
