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[糖尿病患者免疫系统指标的变化]

[Changes in the immune system indices of diabetes mellitus patients].

作者信息

Potemkin V V, Kadagidze Z G, Veskova T K, Derevnina N A, Danilov K Iu

出版信息

Probl Endokrinol (Mosk). 1986 Jan-Feb;32(1):3-5.

PMID:3485281
Abstract

A decrease in the amount of T-lymphocytes and the total amount of lymphocytes in the peripheral blood occurs in diabetes mellitus patients with hyperglycemia over 150 mg%; a decrease in the amount of T-active lymphocytes occurs but in 350 mg% and upwards. A decrease in the amount of B-lymphocytes is noted in hyperglycemia over 200 mg%. The reaction of blast-cell transformation is sharply suppressed in a grave form of diabetes mellitus whereas in moderately grave conditions its decrease is less noticeable. It is assumed that disorder of cellular immunity can be one of the factors contributing to the development of pyoseptic diseases in diabetes mellitus patients.

摘要

血糖超过150毫克%的糖尿病患者外周血中T淋巴细胞数量及淋巴细胞总数减少;血糖在350毫克%及以上时,T活性淋巴细胞数量减少。血糖超过200毫克%时,B淋巴细胞数量减少。在重度糖尿病时,母细胞转化反应明显受抑,而在中度重度情况下,其降低不太明显。据推测,细胞免疫紊乱可能是糖尿病患者发生脓性败血症的因素之一。

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