Department of Orthopaedic and Trauma Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
IFOM-Institute for Research in Operative Medicine, University Witten/Herdecke, Faculty of Health, Cologne, Germany.
Sci Rep. 2021 Dec 1;11(1):23263. doi: 10.1038/s41598-021-02771-5.
Thoracic trauma has decisive influence on the outcome of multiply-injured patients and is often associated with clavicle fractures. The affected patients are prone to lung dysfunction and multiple organ failure. A multi-center, retrospective analysis of patient records documented in the TraumaRegister DGU was performed to assess the influence of surgical stabilization of clavicle fractures in patients with thoracic trauma. A total of 3,209 patients were included in the analysis. In 1362 patients (42%) the clavicle fracture was treated operatively after 7.1 ± 5.3 days. Surgically treated patients had a significant reduction in lung failure (p = 0.013, OR = 0.74), multiple organ failure (p = 0.001, OR = 0.64), intubation time (p = 0.004; -1.81 days) and length of hospital stay (p = 0.014; -1.51 days) compared to non-operative treatment. Moreover, surgical fixation of the clavicle within five days following hospital admission significantly reduced the rates of lung failure (p = 0.01, OR = 0.62), multiple organ failure (p = 0.01, OR = 0.59) and length of hospital stay (p = 0.01; -2.1 days). Based on our results, multiply-injured patients with thoracic trauma and concomitant clavicle fracture may benefit significantly from surgical stabilization of a clavicle fracture, especially when surgery is performed within the first five days after hospital admission.
胸部创伤对多发伤患者的预后有决定性影响,常伴有锁骨骨折。受影响的患者易发生肺功能障碍和多器官衰竭。对 TraumaRegister DGU 中记录的患者病历进行了一项多中心回顾性分析,以评估手术稳定锁骨骨折对胸部创伤患者的影响。共有 3209 名患者纳入分析。在 1362 名患者(42%)中,锁骨骨折在 7.1±5.3 天后接受了手术治疗。与非手术治疗相比,手术治疗的患者肺衰竭(p=0.013,OR=0.74)、多器官衰竭(p=0.001,OR=0.64)、插管时间(p=0.004;-1.81 天)和住院时间(p=0.014;-1.51 天)显著减少。此外,在入院后 5 天内对锁骨进行手术固定可显著降低肺衰竭(p=0.01,OR=0.62)、多器官衰竭(p=0.01,OR=0.59)和住院时间(p=0.01;-2.1 天)的发生率。基于我们的结果,患有胸部创伤和伴随锁骨骨折的多发伤患者可能会从锁骨骨折的手术稳定中显著获益,特别是当手术在入院后 5 天内进行时。