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吻合口漏的诊断

Diagnosis of Anastomotic Leak.

作者信息

Hernandez Paul T, Paspulati Raj M, Shanmugan Skandan

机构信息

Division of Colorectal Surgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

Department of Radiology, University Hospitals, Case Western Reserve University, Cleveland, Ohio.

出版信息

Clin Colon Rectal Surg. 2021 Nov 23;34(6):391-399. doi: 10.1055/s-0041-1735270. eCollection 2021 Nov.

DOI:10.1055/s-0041-1735270
PMID:34853560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610633/
Abstract

Anastomotic leaks after colorectal surgery is associated with increased morbidity and mortality. Understanding the impact of anastomotic leaks and their risk factors can help the surgeon avoid any modifiable pitfalls. The diagnosis of an anastomotic leak can be elusive but can be discerned by the patient's global clinical assessment, adjunctive laboratory data and radiological assessment. The use of inflammatory markers such as C-Reactive Protein and Procalcitonin have recently gained traction as harbingers for a leak. A CT scan and/or a water soluble contrast study can further elucidate the location and severity of a leak. Further intervention is then individualized on the spectrum of simple observation with resolution or surgical intervention.

摘要

结直肠手术后的吻合口漏与发病率和死亡率的增加相关。了解吻合口漏的影响及其危险因素有助于外科医生避免任何可改变的陷阱。吻合口漏的诊断可能难以捉摸,但可以通过患者的整体临床评估、辅助实验室数据和影像学评估来识别。使用炎症标志物如C反应蛋白和降钙素原作为漏出的预兆最近受到了关注。CT扫描和/或水溶性造影剂研究可以进一步阐明漏出的位置和严重程度。然后根据单纯观察至病情缓解或手术干预的范围进行个体化的进一步干预。

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Diagnosis of Anastomotic Leak.吻合口漏的诊断
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本文引用的文献

1
Laparoscopic surgery may decrease the risk of clinical anastomotic leakage and a nomogram to predict anastomotic leakage after anterior resection for rectal cancer.腹腔镜手术可能会降低临床吻合口漏的风险,以及一种用于预测直肠癌前切除术后吻合口漏的列线图。
Int J Colorectal Dis. 2019 Feb;34(2):319-328. doi: 10.1007/s00384-018-3199-z. Epub 2018 Nov 23.
2
Male sex and history of ischemic heart disease are major risk factors for anastomotic leakage after laparoscopic anterior resection in patients with rectal cancer.男性性别和缺血性心脏病史是直肠癌患者腹腔镜前切除术后吻合口漏的主要危险因素。
BMC Gastroenterol. 2018 Jul 17;18(1):117. doi: 10.1186/s12876-018-0846-3.
3
The American Society of Anesthesiologists score influences on postoperative complications and total hospital charges after laparoscopic colorectal cancer surgery.美国麻醉医师协会评分对腹腔镜结直肠癌手术后的术后并发症及医院总费用的影响。
Medicine (Baltimore). 2018 May;97(18):e0653. doi: 10.1097/MD.0000000000010653.
4
Anastomotic Leaks After Small- and Large-Bowel Surgery: Diagnostic Performance of CT and the Importance of Intraluminal Contrast Administration.小肠和大肠手术后的吻合口漏:CT 的诊断性能和腔内对比剂给药的重要性。
AJR Am J Roentgenol. 2018 Jun;210(6):1259-1265. doi: 10.2214/AJR.17.18642. Epub 2018 Apr 9.
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Systematic review and meta-analysis of the use of serum procalcitonin levels to predict intra-abdominal infections after colorectal surgery.血清降钙素原水平用于预测结直肠手术后腹腔内感染的系统评价和荟萃分析。
Int J Colorectal Dis. 2018 Feb;33(2):171-180. doi: 10.1007/s00384-017-2956-8. Epub 2018 Jan 5.
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Asian J Endosc Surg. 2018 Aug;11(3):220-226. doi: 10.1111/ases.12439. Epub 2017 Dec 12.
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Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy.降钙素原:一种用于脓毒症和抗生素治疗的有前景的诊断标志物。
J Intensive Care. 2017 Aug 3;5:51. doi: 10.1186/s40560-017-0246-8. eCollection 2017.
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Multicenter analysis of risk factors for anastomotic leakage after middle and low rectal cancer resection without diverting stoma: a retrospective study of 319 consecutive patients.无转流造口的中低位直肠癌切除术后吻合口漏危险因素的多中心分析:对319例连续患者的回顾性研究
Int J Colorectal Dis. 2017 Oct;32(10):1431-1437. doi: 10.1007/s00384-017-2875-8. Epub 2017 Aug 2.