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性别对骨盆骨折后临床结局的影响。

The impact of gender on clinical outcomes after sustaining a pelvic fracture.

作者信息

Soliman Sara S, Gaccione Amanda G, Bilaniuk Jaroslaw W, Adams John M, DiFazio Louis T, Hakakian Daniel, Kong Karen, Rolandelli Rolando H, Nemeth Zoltan H

机构信息

Department of Surgery, Morristown Medical Center, 100 Madison Ave. #88, Morristown, NJ, 07960, USA.

Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, 10032, USA.

出版信息

Eur J Orthop Surg Traumatol. 2023 Jan;33(1):177-183. doi: 10.1007/s00590-021-03163-1. Epub 2021 Dec 2.

Abstract

INTRODUCTION

In trauma care, pelvic fractures contribute to morbidity and mortality. Since men and women have different pelvic structures and hormonal milieu, we studied if these gender differences affect clinical outcomes after pelvic fractures.

METHODS

Using the 2016 American College of Surgeons Trauma Quality Improvement Program (ACS TQIP) database, we stratified 24,425 patients with pelvic fractures by gender. Male and female patients were analyzed for differences in comorbidities,  mechanism of injury, complications, and other clinical parameters.

RESULTS

Female patients were older (p < 0.001) and had more comorbidities (p < 0.001), such as bleeding disorder, congestive heart failure, chronic obstructive pulmonary disorder, dementia, chronic renal failure, diabetes mellitus, and hypertension. Although female patients were sicker before sustaining pelvic fractures, male patients had higher rates of post-trauma complications (p < 0.001), such as acute kidney injury, deep vein thrombosis, unplanned admission to the intensive care unit (ICU), and unplanned return to the operating room (OR). Multivariate logistic regression further supports this as male gender was independently associated with a 26.1% higher risk of developing at least one complication (p < 0.001), despite having a higher average Injury Severity Score (ISS) (21.91 ± 0.09 versus 20.71 ± 0.11, p < 0.001). Interestingly, male patients also had a longer hospital length of stay than female patients (13.36 ± 0.12 days versus 11.8 ± 0.14 days, p < 0.001).

CONCLUSION

Even though female patients were older and had more pre-existing comorbidities, male patients developed more complications and had longer hospital stays. Trial registration number Not a clinical trial.

摘要

引言

在创伤护理中,骨盆骨折会导致发病和死亡。由于男性和女性的骨盆结构和激素环境不同,我们研究了这些性别差异是否会影响骨盆骨折后的临床结果。

方法

利用2016年美国外科医师学会创伤质量改进项目(ACS TQIP)数据库,我们按性别对24425例骨盆骨折患者进行了分层。分析了男性和女性患者在合并症、损伤机制、并发症及其他临床参数方面的差异。

结果

女性患者年龄较大(p<0.001),合并症较多(p<0.001),如出血性疾病、充血性心力衰竭、慢性阻塞性肺疾病、痴呆、慢性肾衰竭、糖尿病和高血压。尽管女性患者在骨盆骨折前病情较重,但男性患者创伤后并发症发生率较高(p<0.001),如急性肾损伤、深静脉血栓形成、意外入住重症监护病房(ICU)和意外返回手术室(OR)。多因素逻辑回归进一步支持了这一点,尽管男性平均损伤严重程度评分(ISS)较高(21.91±0.09对vs20.71±0.11,p<0.001),但男性性别与发生至少一种并发症的风险独立相关,风险高出26.1%(p<0.001)。有趣的是,男性患者的住院时间也比女性患者长(13.36±0.12天对11.8±0.14天,p<0.001)。

结论

尽管女性患者年龄较大且原有合并症较多,但男性患者出现的并发症更多,住院时间更长。试验注册号:非临床试验。

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