阴道加德纳菌与宫颈镶嵌式阴道镜图像：偶然关联还是因果关系？

Gardnerella vaginalis and mosaic colposcopic pattern of the cervix: casual or causal association?

作者信息

Gonzalez-Falcó J, Jurado M, Madamba A M, Oriol A

出版信息

Gynecol Obstet Invest. 1986;21(2):108-10. doi: 10.1159/000298937.

Abstract

We made a retrospective study of the flora found in the vaginal smears of sexually active women who presented with a mosaic colposcopic pattern of the uterine cervix in an attempt to study some of its epidemiologic factors. Of the 195 cervicovaginal cytologies of patients with mosaic, 61 revealed an abnormal flora (31.2%) while of the 9,856 patients without mosaic, only 2,234 cytologies had an abnormal flora (22.7%) demonstrating a statistically significant higher frequency (p less than 0.0001) of an abnormal flora in women with a mosaic pattern on the cervix. A statistically significant association (p less than 0.02) was encountered between the presence of Gardnerella vaginalis and the mosaic colposcopic pattern, and surprisingly a statistically greater frequency (p less than 0.05) of biopsied dysplasias in the same group. At the moment we can interpret these observations as nothing more than interesting initial findings.

摘要

我们对有性生活的女性阴道涂片菌群进行了回顾性研究，这些女性子宫颈呈现镶嵌式阴道镜图像，目的是研究其中一些流行病学因素。在195例有镶嵌式图像患者的宫颈阴道细胞学检查中，61例显示菌群异常（31.2%），而在9856例无镶嵌式图像的患者中，只有2234例细胞学检查显示菌群异常（22.7%），这表明宫颈呈现镶嵌式图像的女性中，菌群异常的频率在统计学上显著更高（p小于0.0001）。在阴道加德纳菌的存在与镶嵌式阴道镜图像之间存在统计学上的显著关联（p小于0.02），令人惊讶的是，同一组中活检发育异常的频率在统计学上更高（p小于0.05）。目前，我们只能将这些观察结果解释为有趣的初步发现。