Department of Nephrology, Oslo University Hospital.
Section for Cardiovascular and Renal Research, Oslo University Hospital.
Blood Press Monit. 2022 Apr 1;27(2):139-146. doi: 10.1097/MBP.0000000000000577.
Pulse arrival time (PAT) is a potential main feature in cuff-less blood pressure (BP) monitoring. However, the precise relationship between BP parameters and PAT under varying conditions lacks a complete understanding. We hypothesize that simple test protocols fail to demonstrate the complex relationship between PAT and both SBP and DBP. Therefore, this study aimed to investigate the correlation between PAT and BP during two exercise modalities with differing BP responses using an unobtrusive wearable device.
Seventy-five subjects, of which 43.7% had a prior diagnosis of hypertension, participated in an isometric and dynamic exercise test also including seated periods of rest prior to, in between and after. PAT was measured using a prototype wearable chest belt with a one-channel electrocardiogram and a photo-plethysmography sensor. Reference BP was measured auscultatory.
Mean individual correlation between PAT and SBP was -0.82 ± 0.14 in the full protocol, -0.79 ± 0.27 during isometric exercise and -0.77 ± 0.19 during dynamic exercise. Corresponding correlation between PAT and DBP was 0.25 ± 0.35, -0.74 ± 0.23 and 0.39 ± 0.41.
The results confirm PAT as a potential main feature to track changes in SBP. The relationship between DBP and PAT varied between exercise modalities, with the sign of the correlation changing from negative to positive between type of exercise modality. Thus, we hypothesize that simple test protocols fail to demonstrate the complex relationship between PAT and BP with emphasis on DBP.
脉搏到达时间（PAT）是无袖带血压（BP）监测的一个潜在主要特征。然而，在不同条件下 BP 参数与 PAT 之间的精确关系仍缺乏全面了解。我们假设简单的测试方案无法展示 PAT 与 SBP 和 DBP 之间的复杂关系。因此，本研究旨在使用一种非侵入性可穿戴设备，研究两种具有不同血压反应的运动模式下 PAT 与 BP 之间的相关性。
75 名受试者参与了本研究，其中 43.7%的受试者有高血压病史。研究包括等长运动和动态运动测试，在运动前、运动中和运动后分别进行坐姿休息。使用带有单通道心电图和光体积描记传感器的原型可穿戴胸带测量 PAT。参考 BP 使用听诊法测量。
在完整方案中，PAT 与 SBP 的个体平均相关性为 -0.82 ± 0.14，在等长运动中为 -0.79 ± 0.27，在动态运动中为 -0.77 ± 0.19。PAT 与 DBP 的相应相关性为 0.25 ± 0.35、-0.74 ± 0.23 和 0.39 ± 0.41。
研究结果证实 PAT 是跟踪 SBP 变化的一个潜在主要特征。在不同的运动模式下，DBP 与 PAT 之间的关系也不同，运动模式类型的变化导致相关性的符号从负变为正。因此，我们假设简单的测试方案无法展示 PAT 与 BP 之间的复杂关系，尤其是 DBP。
