School of Materials and Physics, China University of Mining and Technology, Xuzhou Jiangsu, 221116, People's Republic of China.
School of Mechatronic Engineering, China University of Mining and Technology, Xuzhou Jiangsu, 221116, People's Republic of China.
J Mech Behav Biomed Mater. 2022 Feb;126:104986. doi: 10.1016/j.jmbbm.2021.104986. Epub 2021 Nov 20.
Although the polyether ether ketone (PEEK) has excellent comprehensive properties, its non-antibacterial and low wear-resistant limit the wide application in the field of artificial joint materials. In this paper, Nano-ZnO was generated in situ on the surface of PEEK powder by one-step hydrothermal method, which improved the binding force of Nano-ZnO and PEEK matrix. Then the PEEK-based nanocomposites were prepared by melt blending with the synthesized Nano-ZnO-PEEK powders and PEEK powders. The microstructure, mechanical, biological and tribological properties of PEEK-based nanocomposites were studied. The results showed that the compressive strength of PEEK-based nanocomposites can reach up to 319.2 ± 2.4 MPa. Both PEEK and PEEK-based nanocomposites were non-toxic to cells. Meanwhile, PEEK-based nanocomposites showed good antibacterial activity against E.coli and Staphylococcus aureus, and the antibacterial activity was better with the increase of Nano-ZnO content. In addition, when the Nano-ZnO content was 5%, the wear rate of PEEK-based nanocomposites was about 68% lower than that of pure PEEK materials. Thus, PEEK-based nanocomposites has a dual function of good antibacterial property and excellent wear resistance.
虽然聚醚醚酮（PEEK）具有优异的综合性能，但它没有抗菌性，耐磨性低，限制了其在人工关节材料领域的广泛应用。本文采用一步水热法在 PEEK 粉末表面原位生成纳米氧化锌（Nano-ZnO），提高了 Nano-ZnO 与 PEEK 基体的结合力。然后，采用熔融共混的方法，将合成的 Nano-ZnO-PEEK 粉末和 PEEK 粉末制备成 PEEK 基纳米复合材料。研究了 PEEK 基纳米复合材料的微观结构、力学、生物学和摩擦学性能。结果表明，PEEK 基纳米复合材料的压缩强度可达 319.2±2.4 MPa。PEEK 及其纳米复合材料均对细胞无毒。同时，PEEK 基纳米复合材料对大肠杆菌和金黄色葡萄球菌表现出良好的抗菌活性，且随着 Nano-ZnO 含量的增加，抗菌活性越好。此外，当 Nano-ZnO 含量为 5%时，PEEK 基纳米复合材料的磨损率比纯 PEEK 材料低约 68%。因此，PEEK 基纳米复合材料具有良好的抗菌性能和优异的耐磨性双重功能。
