Research Center for Metallurgy, National Research and Innovation Agency, PUSPIPTEK Gd. 470, South Tangerang, Banten, 15315, Indonesia.
Research Center for Advanced Materials, National Research and Innovation Agency, South Tangerang, Banten, 15315, Indonesia.
Bioprocess Biosyst Eng. 2022 Sep;45(9):1421-1445. doi: 10.1007/s00449-022-02733-9. Epub 2022 May 24.
Rapid transmission of infectious microorganisms such as viruses and bacteria through person-to-person contact has contributed significantly to global health issues. The high survivability of these microorganisms on the material surface enumerates their transmissibility to the susceptible patient. The antimicrobial coating has emerged as one of the most interesting technologies to prevent growth and subsequently kill disease-causing microorganisms. It offers an effective solution a non-invasive, low-cost, easy-in-use, side-effect-free, and environmentally friendly method to prevent nosocomial infection. Among antimicrobial coating, zinc oxide (ZnO) stands as one of the excellent materials owing to zero toxicity, high biocompatibility to human organs, good stability, high abundancy, affordability, and high photocatalytic performance to kill various infectious pathogens. Therefore, this review provides the latest research progress on advanced applications of ZnO nanostructure-based antibacterial coatings for medical devices, biomedical applications, and health care facilities. Finally, future challenges and clinical practices of ZnO-based antibacterial coating are addressed.
微生物（如病毒和细菌）通过人与人之间的接触迅速传播，这对全球健康问题产生了重大影响。这些微生物在材料表面的高存活率说明了它们对易感患者的传染性。抗菌涂层已成为预防生长和随后杀死致病微生物的最有趣技术之一。它提供了一种有效的解决方案，即一种非侵入性、低成本、易于使用、无副作用且环保的方法来预防医院感染。在抗菌涂层中，氧化锌 (ZnO) 因其零毒性、对人体器官的高生物相容性、良好的稳定性、高丰度、可负担性以及对各种感染性病原体的高效光催化性能而成为优秀材料之一。因此，本综述提供了基于 ZnO 纳米结构的抗菌涂层在医疗器械、生物医学应用和卫生保健设施中的先进应用的最新研究进展。最后，讨论了基于 ZnO 的抗菌涂层的未来挑战和临床实践。
