Polman C H, Dijkstra C D, Sminia T, Koetsier J C
J Neuroimmunol. 1986 May;11(3):215-22. doi: 10.1016/0165-5728(86)90005-6.
Inflammatory cells were characterized by immunohistochemistry, utilizing monoclonal antibodies specific for T cell subsets, B cells, Ia-positive cells and cells of the mononuclear phagocyte system, in cryostat sections of central nervous system of Lewis rats, sacrificed during the course of actively induced experimental allergic encephalomyelitis. The present study provides interesting information about the presence and distribution of cells of the monocyte-macrophage lineage in this immunologically mediated disease. Using these monoclonal antibodies different subpopulations of macrophages having varying distribution patterns in the central nervous system can be recognized.
在主动诱导实验性变态反应性脑脊髓炎病程中处死的Lewis大鼠中枢神经系统的低温切片中，利用针对T细胞亚群、B细胞、Ia阳性细胞和单核吞噬细胞系统细胞的单克隆抗体，通过免疫组织化学对炎性细胞进行表征。本研究提供了关于单核巨噬细胞谱系细胞在这种免疫介导疾病中的存在和分布的有趣信息。使用这些单克隆抗体，可以识别在中枢神经系统中具有不同分布模式的巨噬细胞不同亚群。
