Lovisenberg Diaconal University College, Oslo, Norway
Faculty of Health Studies, VID Specialized University, Oslo, Norway.
BMJ Open. 2021 Dec 2;11(12):e048344. doi: 10.1136/bmjopen-2020-048344.
Patients with advanced chronic obstructive pulmonary disease (COPD) experience a great symptom burden. Breathlessness is a very frequently reported symptom that negatively affects all aspects of daily life and could lead to fear of dying. Non-invasive ventilation (NIV) could be an important palliative measure to manage breathlessness in patients with advanced COPD. We decided to conduct a scoping review to attain an overview of the existing research and to identify knowledge gaps. This scoping review aims to systematically map published studies on the use of NIV in the palliative care of COPD patients, including the perspectives and experiences of patients, families and healthcare professionals.
This scoping review will employ the framework of Arksey and O'Malley. The reporting will be guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist. A comprehensive and systematic search strategy will be developed in cooperation with an experienced librarian. Database searches will be conducted in AMED, PEDro, Embase, CINAHL, PsycInfo and MEDLINE in February 2021. Pairs of authors will independently assess studies' eligibility and extract data using a standardised data-charting form. The data will be inductively summarised and organised thematically. The results will be discussed with an advisory board consisting of nurses and physicians from respiratory and intensive care units.
Approval for the workshop with the advisory board has been attained from the Norwegian Centre for Research Data (480222), and approval will be attained from the Personal Data Protection Officers of the participating hospitals. All advisory board participants will sign an informed written consent before participation. The results could contribute to developing the body of evidence on the use of NIV in the palliative care of COPD patients and serve to identify directions for future research.
患有晚期慢性阻塞性肺疾病（COPD）的患者会经历严重的症状负担。呼吸困难是一种经常报告的症状，会对日常生活的各个方面产生负面影响，并可能导致对死亡的恐惧。无创通气（NIV）可能是管理晚期 COPD 患者呼吸困难的重要姑息治疗措施。我们决定进行范围综述，以获得对现有研究的概述，并确定知识空白。本范围综述旨在系统地绘制关于 NIV 在 COPD 患者姑息治疗中的使用的已发表研究，包括患者、家属和医疗保健专业人员的观点和经验。
本范围综述将采用 Arksey 和 O'Malley 的框架。报告将遵循系统评价和荟萃分析扩展的首选报告项目对范围综述清单的指导。将与经验丰富的图书馆员合作制定全面和系统的搜索策略。数据库搜索将于 2021 年 2 月在 AMED、PEDro、Embase、CINAHL、PsycInfo 和 MEDLINE 中进行。作者将独立评估研究的合格性，并使用标准化的数据图表提取数据。将对数据进行归纳总结，并进行主题组织。结果将与由呼吸和重症监护病房的护士和医生组成的咨询委员会进行讨论。
已获得挪威研究数据中心（480222）对咨询委员会研讨会的批准，并且将获得参与医院的个人数据保护官员的批准。所有咨询委员会参与者在参与之前都将签署知情书面同意书。研究结果可能有助于为 NIV 在 COPD 患者姑息治疗中的使用提供更多证据，并为未来研究指明方向。
