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手指短暂性摩擦性黑变病1例报告

A Rare Case of Transient Friction Melanosis of the Finger: A Case Report.

作者信息

Yoon Ji Ha, Jang Ye Ji, Cho Eun Byul, Park Eun Joo, Kim Kwang Ho, Kim Kwang Joong

机构信息

Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.

出版信息

Ann Dermatol. 2021 Dec;33(6):568-571. doi: 10.5021/ad.2021.33.6.568. Epub 2021 Nov 4.

DOI:10.5021/ad.2021.33.6.568
PMID:34858009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8577913/
Abstract

Friction melanosis (FM) is an acquired pigmented disease that is caused by recurrent mechanical stress. There is no previous report explaining the presence of tiny brown-colored particles confined to the corneal layer. We describe a case of a rare form of FM of the finger that showed a relatively transient clinical course. A 17-year-old Korean female presented with a 5-month history of an asymptomatic localized hyperpigmented patch on the tip of the right index finger. The dermoscopic examination revealed homogenous globular pattern, which favored pigmentation over hemorrhage. Histopathologically, hyperkeratosis and acanthosis with lymphohistiocytic infiltration of the superficial dermis were noted on hematoxylin and eosin staining; however, there was neither a definite increase in melanophages in the upper dermis nor melanocytic proliferation in the basal layer. Per high-power field, multiple brown-colored tiny particles were scattered in the corneal layer. The particles were not dyed by Fontana-Masson stain, iron stain, and S-100. We questioned the patient about the presence of irritation and found that she had bought new shoes at the time of the onset. She was habituated to placing her fingers in her shoes while wearing them because they were slightly tight. The lesion disappeared spontaneously a week after the cause of friction was eliminated. Altogether, we encountered a rare form of FM that occurred in a rare location with a transient clinical course. Further cases on pigmentation restricted to finger tips might reveal the origin of the particles.

摘要

摩擦性黑变病(FM)是一种由反复机械性应力引起的后天性色素沉着疾病。此前尚无报告解释局限于角质层的微小棕色颗粒的存在情况。我们描述了一例罕见的手指摩擦性黑变病病例,其临床病程相对短暂。一名17岁韩国女性,右食指指尖出现一个无症状局限性色素沉着斑,病史5个月。皮肤镜检查显示均匀球状模式,提示色素沉着而非出血。组织病理学上,苏木精-伊红染色显示有角化过度和棘层肥厚,浅层真皮有淋巴细胞-组织细胞浸润;然而,真皮上层未见巨噬细胞明显增多,基底层也无黑素细胞增殖。在高倍视野下,角质层散在多个棕色微小颗粒。这些颗粒未被Fontana-Masson染色、铁染色和S-100染色。我们询问患者是否有刺激因素,发现发病时她买了新鞋。由于鞋子有点紧,她习惯在穿鞋时将手指伸进鞋里。在消除摩擦原因一周后,病变自行消失。总之,我们遇到了一种罕见部位、临床病程短暂的罕见摩擦性黑变病形式。更多局限于指尖色素沉着的病例可能会揭示这些颗粒的来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/a2bb662ade27/ad-33-568-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/6300c202ab02/ad-33-568-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/9334a5dafcf5/ad-33-568-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/a2bb662ade27/ad-33-568-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/6300c202ab02/ad-33-568-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/9334a5dafcf5/ad-33-568-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be24/8577913/a2bb662ade27/ad-33-568-g003.jpg

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Efficacy of 15% trichloroacetic Acid and 50% glycolic Acid peel in the treatment of frictional melanosis: a comparative study.15%三氯乙酸和50%乙醇酸焕肤治疗摩擦性黑变病的疗效:一项对比研究。
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[Friction melanosis].[摩擦性黑变病]
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