Sharquie K E, Al-Dorky M K
Department of Dermatology, College of Medicine, University of Baghdad, Iraq.
J Dermatol. 2001 Jan;28(1):12-5. doi: 10.1111/j.1346-8138.2001.tb00079.x.
Seventy-one patients (70 females and one male) were studied. Their ages at presentation ranged from 16-43 years with a mean of 24.4 years. The duration of disease varied from three months to ten years with a median of 2.7 years. All patients were slim and had recorded using a washing agent (Lifa) during bathing with vigorous friction. Family history of the same disease was present in 11 (15.5%) patients. The pigmentation was brown-black with a rippled pattern and showed no contrast under Wood's light. The areas commonly affected were clavicles (71.8%), shins (36.6%), upper back (32.4%), Adam's apple (31%), lateral aspects of the arms (31%) and other areas. The histopathology of biopsies from 24 patients showed marked dermal melanosis. Amyloid deposits in the papillary dermis were present in one patient. This clinical and histopathological picture suggests that this common condition is related to frictional melanosis.
对71例患者（70例女性和1例男性）进行了研究。他们就诊时的年龄在16至43岁之间，平均年龄为24.4岁。病程从3个月到10年不等，中位数为2.7年。所有患者体型均偏瘦，且均记录在洗澡时使用了一种洗涤剂（立白）并大力摩擦。11例（15.5%）患者有同病家族史。色素沉着呈棕黑色，呈波纹状，在伍德灯下无反差。常见受累部位为锁骨（71.8%）、小腿（36.6%）、上背部（32.4%）、喉结（31%）、手臂外侧（31%）及其他部位。24例患者活检的组织病理学显示有明显的真皮黑素沉着。1例患者乳头真皮层有淀粉样沉积。这种临床和组织病理学表现提示这种常见病症与摩擦性黑变病有关。
