Barros D'sa A A, Bloom S R, Baron J H
Gut. 1978 Apr;19(4):315-20. doi: 10.1136/gut.19.4.315.
Somatostatin (cyclic growth-hormone release-inhibiting hormone--GH-RIH) was infused into dogs with gastric fistulae. Somatostatin inhibited gastric acid response to four gastric stimulants--insulin, food, histamine, and pentagastrin. Histamine- and pentagastrin-stimulated pepsins were inhibited similarly to inhibition of acid. Somatostatin inhibited the gastrin response to insulin and food.
将生长抑素(环状生长激素释放抑制激素——GH-RIH)注入患有胃瘘的狗体内。生长抑素抑制胃对四种胃刺激物——胰岛素、食物、组胺和五肽胃泌素的胃酸反应。组胺和五肽胃泌素刺激的胃蛋白酶受到的抑制与胃酸抑制相似。生长抑素抑制胃泌素对胰岛素和食物的反应。