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利用背向散射的线偏振光和圆偏振光通过散射体尺寸和散射系数来区分混浊介质。

Discriminating turbid media by scatterer size and scattering coefficient using backscattered linearly and circularly polarized light.

作者信息

Singh Michael D, Vitkin I Alex

机构信息

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.

出版信息

Biomed Opt Express. 2021 Oct 11;12(11):6831-6843. doi: 10.1364/BOE.438631. eCollection 2021 Nov 1.

DOI:10.1364/BOE.438631
PMID:34858683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8606157/
Abstract

The effects of scatterer size and scattering coefficient on backscattered linearly and circularly polarized light are investigated through Stokes polarimetry. High-SNR polarization modulation/synchronous detection measurements are corroborated by polarization-sensitive Monte Carlo simulations. Circular degree of polarization (DOP) is found to be sensitive to scatterer size, but is equivocal at times due to helicity flipping effects; linear DOP appears to be mostly dependent on the medium scattering coefficient. We exploit these trends to generate a DOP - DOP response surface which clusters turbid samples based on these medium properties. This work may prove useful in biomedicine, for example in noninvasive assessment of epithelial precancer progression.

摘要

通过斯托克斯偏振测量法研究了散射体大小和散射系数对后向散射线性偏振光和圆偏振光的影响。高信噪比偏振调制/同步检测测量结果得到了偏振敏感蒙特卡罗模拟的证实。发现圆偏振度（DOP）对散射体大小敏感，但由于螺旋度翻转效应有时并不明确；线性DOP似乎主要取决于介质散射系数。我们利用这些趋势生成了一个DOP-DOP响应面，该响应面根据这些介质特性对浑浊样品进行聚类。这项工作可能在生物医学中证明是有用的，例如在非侵入性评估上皮癌前病变进展方面。