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血清C反应蛋白和降钙素原在烧伤后脓毒症中的诊断意义

Diagnostic importance of serum C-reactive protein and procalcitonin in sepsis after burn.

作者信息

Yiğit Ebral, Demir Yiğit Yasemin

机构信息

Department of General Surgery, Gazi Yasargil Training and Research Hospital Diyarbakır 21090, Turkey.

Department of Pediatrics, Gazi Yasargil Training and Research Hospital Diyarbakır 21090, Turkey.

出版信息

Int J Burns Trauma. 2021 Oct 15;11(5):391-396. eCollection 2021.

PMID:34858719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610824/
Abstract

INTRODUCTION

In this study, we investigated the usefulness of blood white blood cell (WBC), C-reactive protein (CRP) and Procalcitonin (PCT) levels with a clinical diagnosis of infection in patients with severe burns, with a bacterial culture (+) wound site, in patients with SIRS and sepsis.

MATERIALS AND METHODS

In the study, 23 patients with (+) burn wound culture hospitalized in the intensive care unit of Gazi Yaşargil Training and Research Hospital Burn Center burn between January 2016 and January 2021 were analyzed. While five of these patients were showing symptoms of SIRS. Sepsis was observed in five patients.

RESULTS

From 23 patients, 18 (78.3%) were male, and 5 (21.7%) were female. The majority of our patients were lived in rural areas. The average age of patients was 1,061±17,273 years. The wound culture results of the 23 patients were (+), mostly due to in 21.7% (n=5) and in 21.7% (n=5). PCT and CRP results did not statistically differ in patients with sepsis, SIRS and (+) wound culture.

CONCLUSION

The laboratory biomarkers WBC, CRP and PCT do not have a superior value in determining and monitoring infection processes in patients with serious burns.

摘要

引言

在本研究中,我们调查了血白细胞(WBC)、C反应蛋白(CRP)和降钙素原(PCT)水平在严重烧伤患者、伤口部位细菌培养阳性患者、全身炎症反应综合征(SIRS)患者和脓毒症患者感染临床诊断中的作用。

材料与方法

本研究分析了2016年1月至2021年1月期间在加齐·亚萨尔吉尔培训与研究医院烧伤中心重症监护病房住院的23例烧伤伤口培养阳性患者。其中5例患者出现SIRS症状。5例患者观察到脓毒症。

结果

23例患者中,18例(78.3%)为男性,5例(21.7%)为女性。我们的大多数患者生活在农村地区。患者的平均年龄为1061±17273岁。23例患者的伤口培养结果为阳性,主要原因是21.7%(n = 5)为[此处原文缺失信息],21.7%(n = 5)为[此处原文缺失信息]。脓毒症、SIRS和伤口培养阳性患者的PCT和CRP结果在统计学上无差异。

结论

实验室生物标志物WBC、CRP和PCT在确定和监测严重烧伤患者的感染过程中没有优越价值。

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