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控制烧伤患者的炎症反应。

Curbing inflammation in burn patients.

作者信息

Farina Jayme A, Rosique Marina Junqueira, Rosique Rodrigo G

机构信息

Department of Surgery and Anatomy, Division of Plastic Surgery, School of Medicine of Ribeirão Preto-SP, University of São Paulo, Avenida Bandeirantes 3900, 9.°andar, 14048-900 Ribeirão Preto SP, Brazil.

出版信息

Int J Inflam. 2013;2013:715645. doi: 10.1155/2013/715645. Epub 2013 May 20.

DOI:10.1155/2013/715645
PMID:23762773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3671671/
Abstract

Patients who suffer from severe burns develop metabolic imbalances and systemic inflammatory response syndrome (SIRS) which can result in multiple organ failure and death. Research aimed at reducing the inflammatory process has yielded new insight into burn injury therapies. In this review, we discuss strategies used to curb inflammation in burn injuries and note that further studies with high quality evidence are necessary.

摘要

患有严重烧伤的患者会出现代谢失衡和全身炎症反应综合征(SIRS),这可能导致多器官功能衰竭和死亡。旨在减轻炎症过程的研究为烧伤治疗带来了新的见解。在本综述中,我们讨论了用于抑制烧伤炎症的策略,并指出需要有高质量证据的进一步研究。

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本文引用的文献

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Effect of acute thermal injury in status of serum vitamins, inflammatory markers, and oxidative stress markers: preliminary data.急性热损伤对血清维生素、炎症标志物及氧化应激标志物状态的影响:初步数据
J Burn Care Res. 2013 Mar-Apr;34(2):e87-91. doi: 10.1097/BCR.0b013e31826fc506.
2
Replacement of specific coagulation factors in patients with burn: a review.烧伤患者特定凝血因子的替代治疗:综述。
Burns. 2013 Jun;39(4):543-8. doi: 10.1016/j.burns.2012.12.009. Epub 2013 Jan 9.
3
The effect of hyperbaric oxygen treatment on the healing of burn wounds in nicotinized and nonnicotinized rats.高压氧治疗对尼古丁化和未尼古丁化大鼠烧伤创面愈合的影响。
J Burn Care Res. 2013 Jul-Aug;34(4):e237-43. doi: 10.1097/BCR.0b013e318270092e.
4
Hypothermia in trauma.创伤中的低温
Emerg Med J. 2013 Dec;30(12):989-96. doi: 10.1136/emermed-2012-201883. Epub 2012 Dec 14.
5
The effects of ulinastatin on systemic inflammation, visceral vasopermeability and tissue water content in rats with scald injury.乌司他丁对烫伤大鼠全身炎症反应、内脏血管通透性及组织含水量的影响。
Burns. 2013 Aug;39(5):916-22. doi: 10.1016/j.burns.2012.11.004. Epub 2012 Dec 5.
6
An update review of stem cell applications in burns and wound care.干细胞在烧伤和伤口护理中的应用最新综述。
Indian J Plast Surg. 2012 May;45(2):229-36. doi: 10.4103/0970-0358.101285.
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Moderate systemic hypothermia decreases burn depth progression.中度全身低温可减少烧伤深度进展。
Burns. 2013 May;39(3):436-44. doi: 10.1016/j.burns.2012.07.022. Epub 2012 Nov 11.
8
DNA and inflammatory mediators in bronchoalveolar lavage fluid from children with acute inhalational injuries.急性吸入性损伤患儿支气管肺泡灌洗液中的DNA和炎症介质
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[Comparative study on the effect of restrictive fluid management strategy on the early pulmonary function of patients with severe burn].[限制性液体管理策略对重度烧伤患者早期肺功能影响的对比研究]
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Non-analgesic effects of opioids: peripheral opioid effects on inflammation and wound healing.阿片类药物的非镇痛作用:外周阿片受体对炎症和伤口愈合的影响。
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