Department of Biostatistics, School of Public Health, Peking University, No. 38, Xueyuan Road, Haidian District, Beijing City, 100191, China.
Environ Sci Pollut Res Int. 2022 Apr;29(18):26877-26888. doi: 10.1007/s11356-021-17891-8. Epub 2021 Dec 3.
Based on the complexity of cognitive-related influences and the specificity of Chinese liquor culture, this study aimed to explore the associations and potential interactions between demographic characteristics, alcohol consumption, life and atmospheric environment, and cognitive function in seniors through a comprehensive analysis, in order to provide evidence support and feasible recommendations. The study sample was selected from the Chinese Longitudinal Healthy Longevity Survey, which included 40,583 seniors aged 65-115 years. Data analysis and processing were performed by R 4.0.4. The relationship between the factors and cognition was modeled and analyzed by generalized additive model, and the interaction was explored by combining the ANOVA. The generalized additive model confirmed that alcohol consumption was detrimental to the cognitive status of older adults, especially for liquor (≥ 38°) and beer. The higher the average daily alcohol consumption, the greater the impairment. SO and PM showed the same negative effects. In contrast, life environment factors such as good education, balanced diet, and positive activity participation had a positive effect on cognition in seniors. In addition, interactions between alcohol consumption and average daily alcohol consumption, frequency of vegetable and meat intake, and between open-air activities, and air pollution were also confirmed. Poor lifestyle choices such as alcohol consumption, unbalanced diet, lower activity participation, and air pollution deteriorate cognitive function in seniors. It is recommended that the elderly population should avoid alcohol consumption, maintain a balanced diet, and be physically active. Attention should also be paid to the effects of air quality.
基于认知相关影响的复杂性和中国白酒文化的特殊性,本研究旨在通过综合分析探讨人口统计学特征、饮酒、生活和大气环境与老年人认知功能之间的关联和潜在相互作用,为提供证据支持和可行建议。研究样本选自中国纵向健康长寿调查,共纳入 40583 名 65-115 岁的老年人。采用 R 4.0.4 进行数据分析和处理。通过广义加性模型对因素与认知之间的关系进行建模和分析,并通过方差分析探索交互作用。广义加性模型证实,饮酒对老年人的认知状态有害,尤其是白酒(≥38°)和啤酒。平均日饮酒量越高,损害越大。SO 和 PM 表现出相同的负面影响。相比之下,生活环境因素,如良好的教育、均衡的饮食和积极的活动参与,对老年人的认知有积极影响。此外,还证实了饮酒和平均日饮酒量、蔬菜和肉类摄入频率以及户外活动与空气污染之间的交互作用。不良的生活方式选择,如饮酒、饮食不均衡、活动参与度降低和空气污染,会使老年人的认知功能恶化。建议老年人群体应避免饮酒,保持均衡饮食和积极运动。还应注意空气质量的影响。