结核中的细胞因子风暴及白细胞介素 6 的作用
Cytokine storm in tuberculosis and IL-6 involvement.
机构信息
Institute of Modern Biopharmaceuticals State Key Laboratory, Breeding Base Eco-Environment and Bio-Ressource of the Three Gorges Area, Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University, Chongqing 400700, China.
Institute of Modern Biopharmaceuticals State Key Laboratory, Breeding Base Eco-Environment and Bio-Ressource of the Three Gorges Area, Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University, Chongqing 400700, China.
出版信息
Infect Genet Evol. 2022 Jan;97:105166. doi: 10.1016/j.meegid.2021.105166. Epub 2021 Nov 30.
Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research.
结核病可能是人类最古老的疾病。这些感染引起的并发症或后续死亡通常与细胞因子风暴有关。白细胞介素-6（IL-6）在结核病的免疫反应中起着至关重要的作用。因此，有必要研究一些新的治疗方法来阻断目前正在用于结核分枝杆菌的 IL-6 信号。在这篇综述中，我们研究了 IL-6 在结核病研究中的意义。
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