Glan Clwyd Hospital, Bodelwyddan, UK
Glan Clwyd Hospital, Bodelwyddan, UK.
Clin Med (Lond). 2021 Nov;21(6):e664-e666. doi: 10.7861/clinmed.2021-0579.
A 65-year-old man, who was previously fit and well with no known medical comorbidities, was admitted with symptoms of dysuria, urinary frequency, pyrexia, chills and lethargy. His vitals showed that he was hypotensive, tachycardic and pyrexial. Urine dip was heavily positive for leukocytes and nitrites and had markedly elevated inflammatory markers and mild acute kidney injury. He was commenced on piperacillin/tazobactam. He went on to develop severe left-sided neck swelling and erythema. Ultrasound of the neck with subsequent computed tomography revealed extensive internal jugular vein thrombosis with abscess collection around the vein. Microbiology grew Gram-negative bacilli, later identified as A diagnosis of Lemierre's syndrome was made. The patient was continued on intravenous piperacillin/tazobactam and metronidazole as per sensitivities and later switched to oral metronidazole. He was initiated on warfarin anticoagulation. He made a remarkable recovery and was discharged with outpatient ear, nose and throat and haematology follow-up.
一位 65 岁的男性,既往身体健康,无已知合并症,因尿痛、尿频、发热、寒战和乏力而入院。生命体征显示他低血压、心动过速和发热。尿沉渣检查白细胞和亚硝酸盐呈强阳性,炎症标志物明显升高,并有轻度急性肾损伤。他开始接受哌拉西林/他唑巴坦治疗。随后他出现严重的左侧颈部肿胀和红斑。颈部超声和随后的计算机断层扫描显示广泛的颈内静脉血栓形成,静脉周围有脓肿积聚。微生物培养出革兰氏阴性杆菌,后来鉴定为 诊断为莱姆病综合征。根据药敏试验,患者继续静脉滴注哌拉西林/他唑巴坦和甲硝唑,后来改为口服甲硝唑。他开始接受华法林抗凝治疗。他恢复得非常好,出院后在耳鼻喉科和血液科门诊进行随访。