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Not always as simple as a UTI: An atypical case of Lemierre's syndrome, the forgotten disease.并非总是像尿路感染那么简单:莱姆病的一个非典型病例,被遗忘的疾病。
Clin Med (Lond). 2021 Nov;21(6):e664-e666. doi: 10.7861/clinmed.2021-0579.
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[Throat ache ans swelling of the neck: first symptoms of Lemierre's syndrome].[喉咙疼痛与颈部肿胀:勒米尔综合征的首发症状]
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本文引用的文献

1
sepsis after tonsillitis/pharyngitis.扁桃体炎/咽炎后的脓毒症
BMJ Case Rep. 2019 Jan 29;12(1):e222287. doi: 10.1136/bcr-2017-222287.
2
Lemierre's syndrome.勒米尔综合征
Int J Emerg Med. 2013 Oct 23;6(1):40. doi: 10.1186/1865-1380-6-40.
3
Lemierre syndrome secondary to community-acquired methicillin-resistant Staphylococcus aureus infection associated with cavernous sinus thromboses.继发于社区获得性耐甲氧西林金黄色葡萄球菌感染并伴有海绵窦血栓形成的勒米尔综合征
J Emerg Med. 2013 Feb;44(2):e177-82. doi: 10.1016/j.jemermed.2012.02.075. Epub 2012 Sep 16.
4
Lemierre's syndrome (necrobacillosis).勒米尔综合征(坏死性杆菌病)。
Postgrad Med J. 1999 Mar;75(881):141-4. doi: 10.1136/pgmj.75.881.141.
5
Fusobacterium necrophorum infections: virulence factors, pathogenic mechanism and control measures.坏死梭杆菌感染:毒力因子、致病机制及控制措施
Vet Res Commun. 1996;20(2):113-40. doi: 10.1007/BF00385634.
6
The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection.勒米尔综合征:继发于口咽感染的颈内静脉化脓性血栓性静脉炎。
Medicine (Baltimore). 1989 Mar;68(2):85-94.

并非总是像尿路感染那么简单:莱姆病的一个非典型病例,被遗忘的疾病。

Not always as simple as a UTI: An atypical case of Lemierre's syndrome, the forgotten disease.

机构信息

Glan Clwyd Hospital, Bodelwyddan, UK

Glan Clwyd Hospital, Bodelwyddan, UK.

出版信息

Clin Med (Lond). 2021 Nov;21(6):e664-e666. doi: 10.7861/clinmed.2021-0579.

DOI:10.7861/clinmed.2021-0579
PMID:34862229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8806302/
Abstract

A 65-year-old man, who was previously fit and well with no known medical comorbidities, was admitted with symptoms of dysuria, urinary frequency, pyrexia, chills and lethargy. His vitals showed that he was hypotensive, tachycardic and pyrexial. Urine dip was heavily positive for leukocytes and nitrites and had markedly elevated inflammatory markers and mild acute kidney injury. He was commenced on piperacillin/tazobactam. He went on to develop severe left-sided neck swelling and erythema. Ultrasound of the neck with subsequent computed tomography revealed extensive internal jugular vein thrombosis with abscess collection around the vein. Microbiology grew Gram-negative bacilli, later identified as A diagnosis of Lemierre's syndrome was made. The patient was continued on intravenous piperacillin/tazobactam and metronidazole as per sensitivities and later switched to oral metronidazole. He was initiated on warfarin anticoagulation. He made a remarkable recovery and was discharged with outpatient ear, nose and throat and haematology follow-up.

摘要

一位 65 岁的男性,既往身体健康,无已知合并症,因尿痛、尿频、发热、寒战和乏力而入院。生命体征显示他低血压、心动过速和发热。尿沉渣检查白细胞和亚硝酸盐呈强阳性,炎症标志物明显升高,并有轻度急性肾损伤。他开始接受哌拉西林/他唑巴坦治疗。随后他出现严重的左侧颈部肿胀和红斑。颈部超声和随后的计算机断层扫描显示广泛的颈内静脉血栓形成,静脉周围有脓肿积聚。微生物培养出革兰氏阴性杆菌,后来鉴定为 诊断为莱姆病综合征。根据药敏试验,患者继续静脉滴注哌拉西林/他唑巴坦和甲硝唑,后来改为口服甲硝唑。他开始接受华法林抗凝治疗。他恢复得非常好,出院后在耳鼻喉科和血液科门诊进行随访。