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勒米尔综合征

Lemierre's syndrome.

作者信息

Eilbert Wesley, Singla Nitin

机构信息

Department of Emergency Medicine, University of Illinois, College of Medicine, 1819 West Polk Street, Room 471 CME, Chicago, IL 60612, USA.

出版信息

Int J Emerg Med. 2013 Oct 23;6(1):40. doi: 10.1186/1865-1380-6-40.

DOI:10.1186/1865-1380-6-40
PMID:24152679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4015694/
Abstract

Lemierre's syndrome is a condition characterized by thrombophlebitis of the internal jugular vein and bacteremia caused by primarily anaerobic organisms, following a recent oropharyngeal infection. This has been an uncommon illness in the era of antibiotic therapy, though it has been reported with increasing frequency in the past 15 years. Lemierre's syndrome should be suspected in young healthy patients with prolonged symptoms of pharyngitis followed by symptoms of septicemia or pneumonia, or an atypical lateral neck pain. Diagnosis is often confirmed by identification of thrombophlebitis of the internal jugular vein and growth of anaerobic bacteria on blood culture. Treatment involves prolonged antibiotic therapy occasionally combined with anticoagulation. We review the literature and a case of a child with Lemierre's syndrome.

摘要

勒米尔综合征是一种以内颈静脉血栓性静脉炎和主要由厌氧菌引起的菌血症为特征的疾病,继发于近期的口咽感染。在抗生素治疗时代,这是一种罕见疾病,不过在过去15年中其报告频率呈上升趋势。对于有咽炎长期症状,随后出现败血症或肺炎症状,或非典型颈部侧方疼痛的年轻健康患者,应怀疑患有勒米尔综合征。诊断通常通过确认内颈静脉血栓性静脉炎以及血培养中厌氧菌生长来证实。治疗包括长期抗生素治疗,偶尔联合抗凝治疗。我们回顾了相关文献并报告了一例患有勒米尔综合征的儿童病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0602/4015694/112a4322f38e/1865-1380-6-40-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0602/4015694/112a4322f38e/1865-1380-6-40-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0602/4015694/112a4322f38e/1865-1380-6-40-1.jpg

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本文引用的文献

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2
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Laryngoscope. 2009 Aug;119(8):1552-9. doi: 10.1002/lary.20542.
3
Lemierre's syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey.丹麦的勒米尔综合征及其他播散性坏死梭杆菌感染:一项前瞻性流行病学和临床调查。
Radiol Case Rep. 2025 Apr 12;20(7):3255-3260. doi: 10.1016/j.radcr.2025.03.054. eCollection 2025 Jul.
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Lemierre's Syndrome Following Streptococcus anginosus Pharyngitis: An Unusual Case of a Forgotten Disease.咽峡炎链球菌引起的 Lemierre 综合征:一例被遗忘疾病的罕见病例
Cureus. 2025 Mar 16;17(3):e80658. doi: 10.7759/cureus.80658. eCollection 2025 Mar.
5
Lemierre's syndrome secondary to fusobacterium necrophorum in an immunocompetent patient: A rare case.免疫功能正常患者中由坏死梭杆菌引起的勒米尔综合征:1例罕见病例。
Radiol Case Rep. 2025 Mar 21;20(6):2903-2907. doi: 10.1016/j.radcr.2025.01.048. eCollection 2025 Jun.
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A Rare Presentation of Lemierre's Syndrome Caused by an Atypical Occurrence of Eikenella corrodens.由腐蚀艾肯菌非典型感染引起的勒米耶综合征罕见病例报告
Cureus. 2025 Feb 4;17(2):e78526. doi: 10.7759/cureus.78526. eCollection 2025 Feb.
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Gut Microbes. 2025 Dec;17(1):2458203. doi: 10.1080/19490976.2025.2458203. Epub 2025 Jan 29.
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Early Radiographic Warning Signs of Impending Lemierre's Syndrome.即将发生勒米尔综合征的早期影像学警示征象。
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Review: Known, Emerging, and Remerging Pharyngitis Pathogens.综述:已知、新兴和再现的咽炎病原体。
J Infect Dis. 2024 Oct 23;230(Supplement_3):S173-S181. doi: 10.1093/infdis/jiae391.
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Lemierre's syndrome associated-diabetic ketoacidosis in an elderly female: a case report.老年女性感染性心内膜炎相关糖尿病酮症酸中毒:病例报告
BMC Infect Dis. 2024 Oct 10;24(1):1137. doi: 10.1186/s12879-024-10033-8.
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Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital.一家儿童医院对勒米尔综合征和其他坏死梭杆菌感染的诊断增加。
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