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眼部冲洗作为急诊患者因眼部有异物感而就诊的一线治疗和诊断方法。

Eye irrigation as a first-line treatment and diagnostic method for emergency department patients who complain of ocular foreign bodies.

机构信息

Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, No. 5, Fuxing St., Gueishan Dist., Taoyuan, 333, Taiwan.

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

出版信息

Sci Rep. 2021 Dec 3;11(1):23386. doi: 10.1038/s41598-021-02989-3.

Abstract

This prospective study aimed at determine whether eye irrigation removes ocular foreign bodies (FBs) and whether ocular pain predicts FBs. Emergency department patients complaining of ocular FBs were enrolled. In the irrigation group (n = 52), pain was evaluated with a visual analog scale before and after irrigation, and the presence of FBs was determined under a slit-lamp. In the nonirrigation group (n = 27), the evaluations were performed upon arrival. The corneal FB retention rate was found significantly lower in the irrigation (13/52, 25%) than in the nonirrigation groups (13/27, 48%; P = 0.04). After irrigation, those without FBs had more patients experiencing pain reduction (67%) compared to those with retained FBs (46%; P = 0.14) and had a greater magnitude of change in pain score (mean ± SD, - 2.6 ± 2.7 vs. - 0.7 ± 1.4; P = 0.02). An improvement in ocular pain score ≥ 5 points after irrigation predicted the absence of FBs with a negative predictive value of 100%. Eye irrigation significantly lowered corneal FB retention; if ocular pain decreased considerably, the probability of retained FBs was low, making irrigation-associated pain score reduction a feasible diagnostic method to exclude FB retention without needing specialized ophthalmic examinations.

摘要

这项前瞻性研究旨在确定眼部冲洗是否能去除眼内异物(FBs),以及眼部疼痛是否能预测 FBs。研究纳入了因眼内异物到急诊科就诊的患者。在冲洗组(n=52)中,在冲洗前后使用视觉模拟量表评估疼痛,并用裂隙灯检查确定 FBs 的存在。在非冲洗组(n=27)中,在到达时进行评估。结果发现,冲洗组(13/52,25%)的角膜 FB 残留率明显低于非冲洗组(13/27,48%;P=0.04)。冲洗后,无 FBs 的患者疼痛缓解率(67%)明显高于有残留 FBs 的患者(46%;P=0.14),且疼痛评分的变化幅度更大(平均±SD,-2.6±2.7 与-0.7±1.4;P=0.02)。冲洗后眼痛评分改善≥5 分可预测无 FBs,其阴性预测值为 100%。眼部冲洗可显著降低角膜 FB 残留率;如果眼部疼痛明显减轻,则 FB 残留的可能性较低,因此,冲洗后疼痛评分的降低可作为一种无需专门眼科检查即可排除 FB 残留的可行诊断方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a3/8642417/f8446cb8692c/41598_2021_2989_Fig1_HTML.jpg

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