Wojtys E, Hankin F, Braunstein E, Kaufer H, Palella T
J Rheumatol. 1986 Feb;13(1):205-7.
A case in which only one sibling of an identical, HLA-B27 negative, twin pairing is affected by ankylosing spondylitis is reported. While endogenous variables may predispose certain populations to ankylosing spondylitis, the discordance illustrated in these seronegative monozygotic twins indicates that exogenous factors may certainly influence the development and course of this disease.
据报道，在一对同卵双胞胎中，只有其中一个HLA - B27阴性的同胞患强直性脊柱炎。虽然内源性变量可能使某些人群易患强直性脊柱炎，但这些血清阴性单卵双胞胎中表现出的不一致性表明，外源性因素肯定会影响该疾病的发展和进程。
