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翻译后修饰和转录后修饰的普遍程度如何?

How pervasive are post-translational and -transcriptional modifications?

作者信息

Agatemor Christian, Middleton Sasa Ama Dyese, Toledo Daniela

机构信息

Department of Chemistry, 1301 Memorial Drive, University of Miami, Coral Gables, FL 33146-0431, USA.

Department of Chemistry, 1301 Memorial Drive, University of Miami, Coral Gables, FL 33146-0431, USA.

出版信息

Trends Cell Biol. 2022 Jun;32(6):475-478. doi: 10.1016/j.tcb.2021.11.002. Epub 2021 Dec 1.

Abstract

Cells use post-translational and post-transcription modifications as crucial mechanisms to maintain homeostasis and regulate gene transcription. Recent discoveries demonstrate that these modifications are more pervasive and important than scientists previously posited. Here, we discuss their importance and provide insight to stimulate new research into these modifications.

摘要

细胞利用翻译后修饰和转录后修饰作为维持体内平衡和调节基因转录的关键机制。最近的发现表明,这些修饰比科学家之前所认为的更为普遍和重要。在此,我们讨论它们的重要性,并提供见解以激发对这些修饰的新研究。

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