Gorman J M, Shear M K, Devereux R B, King D L, Klein D F
Psychosom Med. 1986 Mar-Apr;48(3-4):167-71. doi: 10.1097/00006842-198603000-00002.
Although several investigators have found a higher incidence of mitral valve prolapse (MVP) in patients with panic disorder (PD) and agoraphobia with panic attacks (AgP), there are now several conflicting reports. Discrepancy in the rate of echocardiographic diagnosis of MVP in PD/AgP may be due to different criteria used in evaluating the echocardiogram. In this study, 15 echocardiograms performed on patients with PD/AgP were evaluated by two separate expert echocardiographers. Each used his own standard criteria for diagnosing MVP. The first reader diagnosed MVP in 9 of 15 patients with PD/AgP while the second did not diagnose MVP in any of the 15 patients. This substantiates the belief that criteria variance strongly influences estimates of the prevalence of MVP among patients with PD/AgP.
尽管有几位研究者发现惊恐障碍（PD）患者和伴有惊恐发作的广场恐惧症（AgP）患者中二尖瓣脱垂（MVP）的发病率较高，但现在有几份相互矛盾的报告。PD/AgP中MVP的超声心动图诊断率存在差异，可能是由于评估超声心动图时使用的标准不同。在本研究中，两位独立的专业超声心动图医生对15例PD/AgP患者的超声心动图进行了评估。每人都使用自己的标准来诊断MVP。第一位读者在15例PD/AgP患者中诊断出9例患有MVP，而第二位读者在15例患者中均未诊断出MVP。这证实了一种观点，即标准差异强烈影响PD/AgP患者中MVP患病率的估计。
