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COBRA:大都市医院的 COde Blue 回顾性审核。

COBRA: COde Blue Retrospective Audit in a metropolitan hospital.

机构信息

Intensive Care Unit, Alfred Health, Melbourne, Victoria, Australia.

Eastern Health Intensive Care Services, Box Hill Hospital, Eastern Health, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2023 May;53(5):745-752. doi: 10.1111/imj.15637. Epub 2022 Aug 25.

Abstract

BACKGROUND

Inhospital cardiac arrest (IHCA) is an uncommon but challenging problem.

AIMS

To investigate the management and outcomes of IHCA, and to investigate the effect of introducing a medical emergency team (MET) on IHCA prevalence.

METHODS

Retrospective medical record review of 176 adult IHCA episodes at Box Hill Hospital, a university-affiliated public hospital in metropolitan Melbourne, from July 2012 to June 2017. Inpatients receiving cardiopulmonary resuscitation for IHCA, in inpatient wards, intensive care unit, cardiac catheterisation laboratory and operating theatres were included. Data collected included demographics, resuscitation management and outcomes. Average treatment effect (ATE) was derived from margins estimates and linear regression fitted to hospital outcome, adjusted for IHCA factors. An exponentially weighed moving average control chart was used to explore IHCA prevalence over time.

RESULTS

There were 65.3% of IHCA patients who died in hospital. IHCA prevalence was unchanged after the introduction of a dedicated MET service. Factors associated with higher likelihood of survival to discharge were initial cardiac of rhythm ventricular tachycardia (VT) (ATE 0.10 (95% CI = -0.03 to 0.25)) or ventricular fibrillation (VF) (ATE 0.28 (95% CI = 0.11-0.46)), cardiac monitoring at the time of arrest (ATE 0.06 (95%CI = -0.04 to 0.16)) and time to return of spontaneous circulation (ATE 0.023 (95% CI = 0.015-0.031)).

CONCLUSIONS

IHCA is uncommon and is associated with high mortality. IHCA prevalence was unchanged after the introduction of a dedicated MET service. Factors associated with improved survival to hospital discharge were initial rhythm VT or VF, cardiac monitoring and shorter resuscitation times.

摘要

背景

院内心搏骤停(IHCA)是一种不常见但具有挑战性的问题。

目的

调查 IHCA 的管理和结果,并研究引入医疗应急小组(MET)对 IHCA 发生率的影响。

方法

对 2012 年 7 月至 2017 年 6 月在墨尔本大都市附属大学医院 Box Hill 医院的 176 例成人 IHCA 发作进行回顾性病历审查。纳入在住院病房、重症监护病房、心脏导管插入实验室和手术室接受心肺复苏治疗的住院患者。收集的数据包括人口统计学、复苏管理和结果。平均治疗效果(ATE)是通过边际估计和线性回归得出的,调整了 IHCA 因素后,该回归拟合了医院的结果。使用指数加权移动平均控制图来探索 IHCA 随时间的发生率。

结果

有 65.3%的 IHCA 患者在医院死亡。引入专门的 MET 服务后,IHCA 的发生率没有变化。与更高出院生存率相关的因素包括初始心脏节律室性心动过速(VT)(ATE 0.10(95% CI = -0.03 至 0.25))或心室颤动(VF)(ATE 0.28(95% CI = 0.11-0.46))、心搏骤停时的心脏监测(ATE 0.06(95%CI = -0.04 至 0.16))和自主循环恢复时间(ATE 0.023(95% CI = 0.015-0.031))。

结论

IHCA 并不常见,且死亡率较高。引入专门的 MET 服务后,IHCA 的发生率没有变化。与提高出院生存率相关的因素包括初始节律 VT 或 VF、心脏监测和更短的复苏时间。

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