Li Y M, Zhu Y, Zhang J, Xu D X, Liu Y, Liu F, Peng Z Y
Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Zhonghua Yi Xue Za Zhi. 2021 May 11;101(17):1210-1213. doi: 10.3760/cma.j.cn112137-20201201-03232.
Sepsis is a life-threatening multiple organ dysfunction syndrome caused by infection, and kidney is one of the most organs susceptible to injury in sepsis. Critical ill patients with sepsis often suffer from acute kidney injury (AKI) of varying degrees with a high mortality. There are more and more researches on the early identification, pathogenesis, diagnosis and treatment of acute kidney injury in sepsis. In order to improve the understanding and reduce the mortality of acute kidney injury, this review briefly discussed the early identification, physio-pathologic mechanism, treatment, prognosis and follow up.
脓毒症是一种由感染引起的危及生命的多器官功能障碍综合征，肾脏是脓毒症中最易受损的器官之一。脓毒症危重症患者常伴有不同程度的急性肾损伤（AKI），死亡率很高。关于脓毒症急性肾损伤的早期识别、发病机制、诊断和治疗的研究越来越多。为了增进对急性肾损伤的认识并降低其死亡率，本综述简要讨论了急性肾损伤的早期识别、生理病理机制、治疗、预后及随访。
