Xu Weihao, Bai Anying, Huang Xin, Gao Yinghui, Liu Lin
Haikou Cadre's sanitarium of Hainan Military Region, Haikou, China.
Department of Epidemiology and Biostatistics, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Front Aging Neurosci. 2021 Nov 5;13:774167. doi: 10.3389/fnagi.2021.774167. eCollection 2021.
: Sleep is increasingly recognized as an important lifestyle contributor to health; however, its relationship with Motoric cognitive risk syndrome (MCR) is still unclear. The present study aimed to examine the associations between sleep duration, sleep quality, and MCR among community-dwelling Chinese older adults. : We recruited 5,387 participants aged ≥60 years from the China Health and Retirement Longitudinal Study (CHARLS). Sleep-related variables including night sleep duration and sleep quality were assessed self-reported questionnaires. MCR syndrome was defined as cognitive complaints and slow gait speed without dementia or impaired mobility. Multivariate logistic regression analysis was performed to explore the associations between sleep-related variables and MCR after controlling for all potential confounders including demographic characteristics, lifestyle factors, and comorbidities. : We found that sleep duration was significantly associated with MCR, and the multivariate-adjusted odds ratios (OR) were highest for those with the shortest (<6 h = 1.55, 95% = 1.18-2.04) and longest (≥10 h = 1.73, 95% = 1.03-2.91) sleep durations. Moreover, an increasing frequency of self-perceived poor sleep quality was significantly associated with MCR in the adjusted model (3-4 days = 1.58, 95% = 1.16-2.17; 5-7 days = 1.81, 95% = 1.37-2.40). : Our study indicated an inverted U-shaped association between night sleep duration and MCR. Poor sleep quality was also associated with higher odds of MCR in community-dwelling Chinese elders. Longitudinal studies with a larger population size are needed to establish causality in the future and further explore potential action mechanisms.
睡眠越来越被认为是对健康有重要影响的一种生活方式；然而，它与运动认知风险综合征（MCR）之间的关系仍不清楚。本研究旨在探讨社区居住的中国老年人的睡眠时间、睡眠质量与MCR之间的关联。我们从中国健康与养老追踪调查（CHARLS）中招募了5387名年龄≥60岁的参与者。通过自我报告问卷评估包括夜间睡眠时间和睡眠质量在内的睡眠相关变量。MCR综合征被定义为存在认知主诉且步态缓慢，但无痴呆或行动能力受损。在控制了包括人口统计学特征、生活方式因素和合并症在内的所有潜在混杂因素后，进行多变量逻辑回归分析以探讨睡眠相关变量与MCR之间的关联。我们发现睡眠时间与MCR显著相关，睡眠时间最短（<6小时，多变量调整后的比值比[OR]=1.55，95%置信区间[CI]=1.18 - 2.04）和最长（≥10小时，OR = 1.73，95%CI = 1.03 - 2.91）的人群的多变量调整后的比值比最高。此外，在调整模型中，自我感觉睡眠质量差的频率增加与MCR显著相关（3 - 4天，OR = 1.58，95%CI = 1.16 - 2.17；5 - 7天，OR = 1.81，95%CI = 1.37 - 2.40）。我们的研究表明夜间睡眠时间与MCR之间存在倒U形关联。睡眠质量差也与社区居住的中国老年人患MCR的较高几率相关。未来需要进行更大规模人群的纵向研究以确定因果关系并进一步探索潜在的作用机制。
